Myofibroblasts are contractile, α-smooth muscle actin-positive cells with multiple roles in
pathophysiological processes. Myofibroblasts mediate wound contractions, but their …

Since the initial identification of the novel coronavirus SARS-CoV-2 in December 2019, the
COVID-19 pandemic has become a leading cause of morbidity and mortality worldwide. As …

A key component of cardiac ischemia–reperfusion injury (IRI) is the increased generation of
reactive oxygen species, leading to enhanced inflammation and tissue dysfunction in …

Background: Empagliflozin reduces the risk of hospitalization for heart failure in patients with
type 2 diabetes and cardiovascular disease. We sought to elucidate the effect of …

Background—Underlying mechanisms in heart failure (HF) with preserved ejection fraction
remain unknown. We investigated cardiovascular plasma biomarkers in HF with preserved …

Background Heart failure with preserved ejection fraction (HFPEF) is a major health problem
associated with myocardial leukocyte infiltration, inflammation, and fibrosis. Monocyte and …

Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6-PPDQ), a
transformation product of tyre-derived 6-PPD, has been frequently detected in different …

Heart failure with preserved ejection fraction (HFpEF) is a growing public health concern,
with rising incidence alongside high morbidity and mortality. However, the pathophysiology …

Obesity is most commonly defined as a BMI of over 30 kg/m2. Typical classification is into
categories of Class I (BMI> 30 kg/m2), Class II (BMI equal to or over 35 kg/m2) and Class III …

Physicochemical features of a cell nanoenvironment exert important influence on stem cell
behavior and include the influence of matrix elasticity and topography on differentiation …