The human social brain is complex. Current knowledge fails to define the neurobiological
processes underlying social behaviour involving the (patho-) physiological mechanisms that …

Maternal immune activation (mIA) during pregnancy is hypothesised to disrupt offspring
neurodevelopment and predispose offspring to neurodevelopmental disorders such as …

Schizophrenia is a complex and multifactorial disorder generally diagnosed in young adults
at the time of the first psychotic episode of delusions and hallucinations. These positive …

For the past 50 years, the clinical efficacy of antipsychotic medications has relied on
blockade of dopamine D2 receptors. Drug development of non-D2 compounds, seeking to …

Cannabis use disorder (CUD) is widespread, and there is no pharmacotherapy to facilitate
its treatment. AEF0117, the first of a new pharmacological class, is a signaling-specific …

Background Persons with suicidality including suicidal ideation (SI), suicide plans (SP)
and/or suicide attempts (SA) are at higher risk for future suicide than those without …

Neuropsychiatric disorders such as schizophrenia are associated with cognitive impairment,
including learning, memory and attention deficits. Antipsychotic drugs are limited in their …

Schizophrenia is a form of mental disorder that is behaviorally characterized by abnormal
behavior, such as social function deficits or other behaviors that are disconnected from …

Modern neuropsychopharmacology commenced in the 1950s with the serendipitous
discovery of first-generation antipsychotics and antidepressants which were therapeutically …

Exposure to inflammatory stressors during fetal development is a major risk factor for
neurodevelopmental disorders (NDDs) in adult offspring. Maternal immune activation (MIA) …