Place in therapy of anti-IL-17 and 23 in psoriasis according to the severity of comorbidities: a focus on cardiovascular disease and metabolic syndrome

E Trovato, P Rubegni, F Prignano - Expert Opinion on Biological …, 2022 - Taylor & Francis
Introduction Psoriasis is an inflammatory disease nowadays considered not only as a
cutaneous but as a systemic disease. Among the numerous comorbidities, psoriatic arthritis …

Killing two birds with one stone: potential therapies targeting psoriasis and atherosclerosis at the same time

EK Merzel Šabović, M Starbek Zorko… - International Journal of …, 2022 - mdpi.com
Psoriasis is a chronic systemic inflammatory disease. Due to systemic inflammation, it is
associated with many comorbidities. Among them, cardiovascular diseases represent the …

Estimating Type 2 Diabetes Prevalence: A Model of Drug Consumption Data

R Oliveira, M Monteiro-Soares, JP Guerreiro, R Pereira… - Pharmacy, 2024 - mdpi.com
Observational, cross-sectional prevalence studies are costly and time-consuming. The
development of indirect methods estimating prevalence used to obtain faster, less …

Phytochemical investigation, structural elucidation, in silico study and anti-psoriatic activity of potent bioactive from Betula utilis

P Biswasroy, D Pradhan, DK Sahu, V Rai… - Journal of …, 2023 - Taylor & Francis
Psoriasis is a chronic autoimmune pathological condition characterized by hyperactivation
of proinflammatory cytokines (IL-6, TNF-α, IL-17, IL-23, etc.). Severe drug-associated …

The Perspective of Cannabidiol in Psoriasis Therapy

AMA Stanescu, GC Bejan, MD Balta… - … : Targets and Therapy, 2024 - Taylor & Francis
Psoriasis is a chronic skin condition that can significantly impact the quality of life of those
affected. As an autoimmune disease, it can lead to itchy, painful, and scaly patches on the …

The Intersection of the Pathogenic Processes Underlying Psoriasis and the Comorbid Condition of Obesity

E Scala, L Mercurio, C Albanesi, S Madonna - Life, 2024 - mdpi.com
In the past decade, our understanding of psoriasis pathogenesis has made significant steps
forward, leading to the development of multiple game-changing therapies. While psoriasis …

Adenosine 5'monophosphate-activated protein kinase activation reduces the risks of psoriasis and its comorbidities: a Mendelian randomization study in the UK …

Y Xiao, D Jing, G Zhou, Z Tang, C Peng… - …, 2024 - academic.oup.com
Objective Whether metformin and its adenosine 5 'monophosphate-activated protein kinase
(AMPK) activation protect from psoriasis risk is unconcluded. We investigated the effect of …

Effects of biological agents on glycogen metabolism in psoriasis patients: A systematic review and meta‐analysis

T He, Z Chang, Y Zhang, X Lang… - Australasian Journal of …, 2024 - Wiley Online Library
The effectiveness and safety of biological agents for treating psoriasis have been confirmed;
however, their effects on glucose metabolism biomarkers in psoriasis patients remain …

Insulin resistance in patients with psoriasis

IV Pankiv - International Journal of Endocrinology (Ukraine), 2021 - iej.zaslavsky.com.ua
Psoriasis is a chronic systemic inflammatory disease accompanied by an activation of skin
dendritic cells with accumulation in the inflammatory foci of interleukin-23 and activated Th-1 …

Why is it important to know about the implications of alcohol consumption and psoriasis–a mini-review

GC Bejan, IV Grajdeanu, O Nicolescu, AA Simionescu… - diabetes, 2021 - ceeol.com
Psoriasis is a chronic inflammatory disease characterized by aberrant keratinocyte
differentiation and hyperproliferation. In psoriasis, there is an abnormal cross-talk between …