Autophagy is a process that targets various intracellular elements for degradation.
Autophagy can be non-selective—associated with the indiscriminate engulfment of cytosolic …

Mitochondria are the energy center of the cell. They are found in the cell cytoplasm as
dynamic networks where they adapt energy production based on the cell's needs. They are …

Mitochondria are central hubs of cellular metabolism that also play key roles in signaling
and disease. It is therefore fundamentally important that mitochondrial quality and activity …

Mitochondria are essential organelles that execute and coordinate various metabolic
processes in the cell. Mitochondrial dysfunction severely affects cell fitness and contributes …

Autophagy is a highly conserved catabolic process induced under various conditions of
cellular stress, which prevents cell damage and promotes survival in the event of energy or …

That certain cell types in the central nervous system are more likely to undergo
neurodegeneration in Parkinson's disease is a widely appreciated but poorly understood …

The maintenance of a healthy and functional mitochondrial network is critical during
development as well as throughout life in the response to physiological adaptations and …

With the growing prevalence of cardiovascular disease (CVD), there is an urgent need to
explore non-conventional therapeutic measures to alleviate the burden of CVD on global …

Mitochondria are multifunctional subcellular organelles essential for cellular energy
homeostasis and apoptotic cell death. It is, therefore, crucial to maintain mitochondrial …

Autophagy and the ubiquitin–proteasome system (UPS) are the two major intracellular
quality control and recycling mechanisms that are responsible for cellular homeostasis in …