Recent pharmacological advances in the repurposing of artemisinin drugs

Y Meng, N Ma, H Lyu, YK Wong… - Medicinal research …, 2021 - Wiley Online Library
Artemisinins are a family of sesquiterpene lactones originally derived from the sweet
wormwood (Artemisia annua). Beyond their well‐characterized role as frontline antimalarial …

[图书][B] Parasitology: an integrated approach

A Gunn, SJ Pitt - 2022 - books.google.com
Parasitology Highly detailed textbook on parasites and parasite relationships The fully
revised edition of Parasitology: An Integrated Approach holds true to its engaging and easy …

Anti‐Schistosoma mansoni effects of essential oils and their components

MT Islam, M Martorell, B Salehi, WN Setzer… - Phytotherapy …, 2020 - Wiley Online Library
Schistosoma mansoni is endemic in 55 countries around the world. S. mansoni is a water‐
borne parasite of humans belonging to the group of blood flukes. Generally, schistosomiasis …

Antiparasitic properties of 4-nerolidylcatechol from Pothomorphe umbellata (L.) Miq.(Piperaceae) in vitro and in mice models with either prepatent or patent …

D de Souza Costa, CM Leal, RA Cajas… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Roots of Pothomorphe umbellata (L.) Miq. are
used in traditional medicine of Africa and South America for the treatment of malaria and …

Antischistosomal properties of aurone derivatives against juvenile and adult worms of Schistosoma mansoni

VRD Pereira, LS da Silveira, AC Mengarda, IJA Júnior… - Acta Tropica, 2021 - Elsevier
Schistosomiasis is a neglected disease caused by helminth flatworms of the genus
Schistosoma, affecting over 240 million people in more than 70 countries. The treatment …

Oral administration of artemisone for the treatment of schistosomiasis: Formulation challenges and in vivo efficacy

J Zech, D Gold, N Salaymeh, NC Sasson… - Pharmaceutics, 2020 - mdpi.com
Artemisone is an innovative artemisinin derivative with applications in the treatment of
malaria, schistosomiasis and other diseases. However, its low aqueous solubility and …

In vitro and in vivo evaluation of cnicin from blessed thistle (Centaurea benedicta) and its inclusion complexes with cyclodextrins against Schistosoma mansoni

LS Queiroz, EA Ferreira, AC Mengarda… - Parasitology …, 2021 - Springer
Schistosomiasis, caused by a blood fluke of the genus Schistosoma, afflicts over 230 million
people worldwide. Treatment of the disease relies on just one drug, praziquantel. Cnicin …

Therapeutic potential of natural products in schistosomiasis-associated liver fibrosis

C Liu, D Fisher, K Pronyuk, E Musabaev… - Frontiers in …, 2024 - frontiersin.org
Schistosomiasis is a parasitic disease that endangers human health and social
development. The granulomatous reaction of Schistosoma eggs in the liver is the main …

Effect of Praziquantel on Schistosoma mekongi Proteome and Phosphoproteome

P Chienwichai, S Ampawong, P Adisakwattana… - Pathogens, 2020 - mdpi.com
Schistosoma mekongi causes schistosomiasis in southeast Asia, against which praziquantel
(PZQ) is the only treatment option. PZQ resistance has been reported, thus increasing the …

Design, synthesis, and antitumor activities of isomers of artemisinin dimer derivatives

L Yue, Y Pan, J Wang, L Yue, Y Luo, F Lv… - Chemistry & …, 2023 - Wiley Online Library
In recent years, numerous studies have reported on the anti‐tumor properties of artemisinin
and its derivatives. However, the relationship between their artemisinin chirality and activity …