Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the
second most prevalent aortic disease following atherosclerosis, representing the ninth …

The problem of inadequate statistical reporting is long standing and widespread in the
biomedical literature, including in cardiovascular physiology. Although guidelines for …

Objectives This study aimed to identify key AAA-related m1A RNA methylation regulators
and their association with immune infiltration in AAA. Furthermore, we aimed to explore the …

Clonal expansion refers to the proliferation and selection of advantageous “clones” that are
better suited for survival in a Darwinian manner. In recent years, we have greatly enhanced …

Thoracic aortopathy–aneurysm, dissection, and rupture–is increasingly responsible for
significant morbidity and mortality. Advances in medical genetics and imaging have …

Abdominal aortic aneurysms (AAAs) are highly lethal cardiovascular diseases without
effective medications. However, the molecular and signaling mechanisms remain unclear. A …

Abdominal aortic aneurysm (AAA) remains a lethal aortic disease in the elderly. Currently,
no effective drugs can be clinically applied to prevent the development of AAA. Herein, a …

Abdominal aortic aneurysm (AAA) was previously ascribed to weaken defective medial
arterial/adventitial layers, for example, smooth muscle/fibroblast cells. Therefore, besides …

Inflammation and activation of the immune system are key molecular and cellular events in
the pathogenesis of cardiovascular diseases, including atherosclerosis, hypertension …

Objective The purpose of this study was to investigate whether rapamycin inhibits the
development of thoracic aortic aneurysm and dissection (TAAD) in mice. Methods Three …