Exopolysaccharides of Lactobacillus rhamnosus GG ameliorate Salmonella typhimurium-induced intestinal inflammation via the TLR4/NF-κB/MAPK pathway

J Li, Q Li, Q Wu, N Gao, Z Wang, Y Yang… - Journal of Animal Science …, 2023 - Springer
Background Salmonella typhimurium (ST), as an important foodborne bacterial pathogen,
can cause diarrhea and gastroenteritis in humans and animals. Numerous studies have …

TRAF6 promotes the progression and growth of colorectal cancer through nuclear shuttle regulation NF-kB/c-jun signaling pathway

G Zhu, Z Cheng, Y Huang, W Zheng, S Yang, C Lin… - Life sciences, 2019 - Elsevier
Aims TRAF6 is an intracellular signal adapter molecule plays a significant role in tumor
development. However, the specific mechanism causes and promotes of colorectal cancer …

Pasteurella multocida Pm0442 Affects Virulence Gene Expression and Targets TLR2 to Induce Inflammatory Responses

F He, X Qin, N Xu, P Li, X Wu, L Duan, Y Du… - Frontiers in …, 2020 - frontiersin.org
Pasteurella multocida is an important pathogenic bacterium of domestic animals. However,
the mechanisms of infection are still poorly understood. Here, we found that Pm0442 was …

PMCNA_RS00975 activates NF-κB and ERK1/2 through TLR2 and contributes to the virulence of Pasteurella multocida

T Xu, M Kou, P Cao, B Liu, Y Zheng, Q Jiang… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction Pasteurella multocida is a pathogenic bacterium known to cause hemorrhagic
septicemia and pneumonia in poultry. Reports have indicated that certain proteins, either …

Development of novel iron-regulated Pasteurella multocida B: 2 bacterin and refinement of vaccine quality in terms of minimum variation in particle size and …

R Varshney, R Varshney, VK Chaturvedi, M Rawat… - Microbial …, 2020 - Elsevier
To enhance the qualitative bacterial biomass per unit of media and to overcome the
limitations of the existing haemorrhagic septicaemia (HS) vaccines, a comprehensive study …

Experimental pathogenicity and comparative genome analysis of high-and low-virulence strains of rabbit-origin Pasteurella multocida

R Qiu, H Wei, B Hu, M Chen, Y Song, W Xu… - … and Infectious Diseases, 2022 - Elsevier
Pasteurella multocida, the causative pathogen of rabbit pasteurellosis, causes significant
economic losses in the commercial rabbit industry. However, the associated pathogenic …

Potentially functional microRNA-mRNA regulatory networks in intestinal ischemia-reperfusion injury: a bioinformatics analysis

Z Jiang, S Chen, L Zhang, J Shen… - Journal of Inflammation …, 2021 - Taylor & Francis
Background Intestinal ischemia-reperfusion (II/R) injury is a common clinical complication
associated with high mortality, for which microRNA (miRNA) drives potentially its …

Differences in pathogenicity and virulence-associated gene expression among Pasteurella multocida strains with high and low virulence in a lung tissue model

Y Cheng, K Wang, L Lin, X Zhao, Z Pan, Z Zhou - Microbial pathogenesis, 2020 - Elsevier
Pasteurella multocida capsular type A can cause a pulmonary infection, leading to serious
pecuniary losses in cattle. The heterogeneity of infection outcome of P. multocida strains …

Analyses of transcriptomics upon IL-1β-stimulated mouse chondrocytes and the protective effect of catalpol through the NOD2/NF-κB/MAPK signaling pathway

Y Pang, L Zhao, X Ji, K Guo, X Yin - Molecules, 2023 - mdpi.com
The overall objective of this study was to investigate the mechanism of inflammation on
chondrocyte injury and the protective effect of catalpol on chondrocytes in an inflammatory …

Activation of MyD88-Dependent TLR Signaling Modulates Immune Response of the Mouse Heart during Pasteurella multocida Infection

Q Fu, J Jiang, X Li, Z Zhai, X Wang, C Li, Q Chen… - Microorganisms, 2023 - mdpi.com
Pasteurella multocida (P. multocida) is an important zoonotic pathogen. In addition to lung
lesions, necropsies have revealed macroscopic lesions in the heart in clinical cases …