Asthma remission: what is it and how can it be achieved?

D Thomas, VM McDonald, ID Pavord… - European Respiratory …, 2022 - Eur Respiratory Soc
Asthma treatment goals currently focus on symptom and exacerbation control rather than
remission. Remission is not identical to cure, but is a step closer. This review considers the …

Disease-modifying anti-asthmatic drugs

M Lommatzsch, GG Brusselle, GW Canonica… - The Lancet, 2022 - thelancet.com
Drugs available for asthma treatment in the first decades of the 20th century
(sympathomimetic agents such as oral ephedrine, intravenous adrenaline, or inhaled …

After asthma: redefining airways diseases

ID Pavord, R Beasley, A Agusti, GP Anderson, E Bel… - The Lancet, 2018 - thelancet.com
Executive summary Asthma is responsible for considerable global morbidity and health-care
costs. Substantial progress was made against key outcomes such as hospital admissions …

Allergen immunotherapy in children user's guide

M Alvaro‐Lozano, CA Akdis, M Akdis… - Pediatric allergy and …, 2020 - Wiley Online Library
Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …

Early-life origins of chronic obstructive pulmonary disease

FD Martinez - New England Journal of Medicine, 2016 - Mass Medical Soc
Early-Life Origins of Chronic Obstructive Pulmonary Disease | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …

Risk factors for asthma: is prevention possible?

R Beasley, A Semprini, EA Mitchell - The Lancet, 2015 - thelancet.com
Asthma is one of the most common diseases in the world, resulting in a substantial burden of
disease. Although rates of deaths due to asthma worldwide have reduced greatly over the …

On-Line Analysis of Exhaled Breath: Focus Review

T Bruderer, T Gaisl, MT Gaugg, N Nowak… - Chemical …, 2019 - ACS Publications
On-line analysis of exhaled breath offers insight into a person's metabolism without the need
for sample preparation or sample collection. Due to its noninvasive nature and the possibility …

Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma

P Kachroo, ID Stewart, RS Kelly, M Stav, K Mendez… - Nature medicine, 2022 - nature.com
The application of large-scale metabolomic profiling provides new opportunities for realizing
the potential of omics-based precision medicine for asthma. By leveraging data from over …

Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome

J Lötvall, CA Akdis, LB Bacharier, L Bjermer… - Journal of Allergy and …, 2011 - Elsevier
It is increasingly clear that asthma is a complex disease made up of number of disease
variants with different underlying pathophysiologies. Limited knowledge of the mechanisms …

International consensus on (ICON) pediatric asthma

NG Papadopoulos, H Arakawa, KH Carlsen… - Allergy, 2012 - Wiley Online Library
Asthma is the most common chronic lower respiratory disease in childhood throughout the
world. Several guidelines and/or consensus documents are available to support medical …