Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
formation of plaques containing lipid, connective tissue and immune cells in the intima of …
Targeting inflammation in atherosclerosis—from experimental insights to the clinic
O Soehnlein, P Libby - Nature reviews Drug discovery, 2021 - nature.com
Atherosclerosis, a dominant and growing cause of death and disability worldwide, involves
inflammation from its inception to the emergence of complications. Targeting inflammatory …
inflammation from its inception to the emergence of complications. Targeting inflammatory …
Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities
G Hajishengallis, T Chavakis - Nature Reviews Immunology, 2021 - nature.com
Periodontitis, a major inflammatory disease of the oral mucosa, is epidemiologically
associated with other chronic inflammation-driven disorders, including cardio-metabolic …
associated with other chronic inflammation-driven disorders, including cardio-metabolic …
Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities
Atherosclerosis is a lipid-driven inflammatory disease of the arterial intima in which the
balance of pro-inflammatory and inflammation-resolving mechanisms dictates the final …
balance of pro-inflammatory and inflammation-resolving mechanisms dictates the final …
Mechanisms underlying the association between periodontitis and atherosclerotic disease
Atherosclerosis is central to the pathology of cardiovascular diseases, a group of diseases in
which arteries become occluded with atheromas that may rupture, leading to different …
which arteries become occluded with atheromas that may rupture, leading to different …
Monocyte-macrophages and T cells in atherosclerosis
I Tabas, AH Lichtman - Immunity, 2017 - cell.com
Atherosclerosis is an arterial disease process characterized by the focal subendothelial
accumulation of apolipoprotein-B-containing lipoproteins, immune and vascular wall cells …
accumulation of apolipoprotein-B-containing lipoproteins, immune and vascular wall cells …
Endothelial cell dysfunction and the pathobiology of atherosclerosis
MA Gimbrone Jr, G García-Cardeña - Circulation research, 2016 - Am Heart Assoc
Dysfunction of the endothelial lining of lesion-prone areas of the arterial vasculature is an
important contributor to the pathobiology of atherosclerotic cardiovascular disease …
important contributor to the pathobiology of atherosclerotic cardiovascular disease …
Macrophage phenotype and function in different stages of atherosclerosis
I Tabas, KE Bornfeldt - Circulation research, 2016 - Am Heart Assoc
The remarkable plasticity and plethora of biological functions performed by macrophages
have enticed scientists to study these cells in relation to atherosclerosis for> 50 years, and …
have enticed scientists to study these cells in relation to atherosclerosis for> 50 years, and …
Inflammation as a link between periodontal disease and obesity
F Pamuk, A Kantarci - Periodontology 2000, 2022 - Wiley Online Library
Nutrition plays a critical role in the homeostatic balance, maintenance of health, and
longevity. There is a close link between inflammatory diseases and nutritional health …
longevity. There is a close link between inflammatory diseases and nutritional health …
[HTML][HTML] Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms
CN Serhan - The FASEB Journal, 2017 - ncbi.nlm.nih.gov
Practitioners of ancient societies from the time of Hippocrates and earlier recognized and
treated the signs of inflammation, heat, redness, swelling, and pain with agents that block or …
treated the signs of inflammation, heat, redness, swelling, and pain with agents that block or …