Indole–a promising pharmacophore in recent antiviral drug discovery
A Dorababu - RSC Medicinal Chemistry, 2020 - pubs.rsc.org
The bicyclic molecule indole has been in the limelight because of its numerous
pharmacological potencies. It is used as an excellent scaffold in drug discovery of medicinal …
pharmacological potencies. It is used as an excellent scaffold in drug discovery of medicinal …
Prospects for developing an hepatitis C virus E1E2‐based nanoparticle vaccine
EA Toth, AK Andrianov… - Reviews in Medical …, 2023 - Wiley Online Library
Globally, more than 58 million people are chronically infected with Hepatitis C virus (HCV)
with 1.5 million new infections occurring each year. An effective vaccine for HCV is therefore …
with 1.5 million new infections occurring each year. An effective vaccine for HCV is therefore …
Diversity in a honey bee pathogen: first report of a third master variant of the Deformed Wing Virus quasispecies
Abstract Treatment of emerging RNA viruses is hampered by the high mutation and
replication rates that enable these viruses to operate as a quasispecies. Declining honey …
replication rates that enable these viruses to operate as a quasispecies. Declining honey …
[PDF][PDF] Clinical course of infection and viral tissue tropism of hepatitis C virus–like nonprimate hepaciviruses in horses
S Pfaender, JMV Cavalleri, S Walter… - …, 2015 - Wiley Online Library
Hepatitis C virus (HCV) has a very narrow species and tissue tropism and efficiently
replicates only in humans and the chimpanzee. Recently, several studies identified close …
replicates only in humans and the chimpanzee. Recently, several studies identified close …
Exploring NS3/4A, NS5A and NS5B proteins to design conserved subunit multi-epitope vaccine against HCV utilizing immunoinformatics approaches
Hepatitis C virus (HCV) vaccines, designed to augment specific T-cell responses, have been
designated as an important aspect of effective antiviral treatment. However, despite the …
designated as an important aspect of effective antiviral treatment. However, despite the …
The epidemiology of hepatitis B and hepatitis C infections in China from 2004 to 2014: an observational population‐based study
Viral hepatitis is a major public health concern in China, but data on national
epidemiological characteristics are lacking. We collected reporting incidence data on …
epidemiological characteristics are lacking. We collected reporting incidence data on …
Small molecule NS5B RdRp non-nucleoside inhibitors for the treatment of HCV infection: A medicinal chemistry perspective
Z Zhou, J Zhang, E Zhou, C Ren, J Wang… - European Journal of …, 2022 - Elsevier
Hepatitis C virus (HCV) infection has become a global health problem with enormous risks.
Nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp) is a component …
Nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp) is a component …
Chronic viral hepatitis: policy, regulation, and strategies for its control and elimination in Ethiopia
F Shiferaw, M Letebo, A Bane - BMC Public Health, 2016 - Springer
Abstract Background Hepatitis B and C are silent killers not yet recognized as major public
health challenges in many developing countries with huge disease burden. In Ethiopia …
health challenges in many developing countries with huge disease burden. In Ethiopia …
[HTML][HTML] Exploring HCV genome to construct multi-epitope based subunit vaccine to battle HCV infection: Immunoinformatics based approach
Abstract Hepatitis C Virus (HCV) infection is a major cause of chronic liver disease,
hepatocellular carcinoma, and the single most common indication for liver transplantation …
hepatocellular carcinoma, and the single most common indication for liver transplantation …
Functional nanomaterials can optimize the efficacy of vaccines
Nanoscale materials can improve the efficacy of vaccines. Herein we review latest
developments that use nanomaterials for vaccines. By highlighting the relationships …
developments that use nanomaterials for vaccines. By highlighting the relationships …