Half a century since their discovery by Llinás and colleagues, dendritic spikes have been
observed in various neurons in different brain regions, from the neocortex and cerebellum to …

Summary Layer 1 (L1) of the neocortex acts as a nexus for the collection and processing of
widespread information. By integrating ascending inputs with extensive top-down activity …

Large portions of the thalamus receive strong driving input from cortical layer 5 (L5) neurons
but the role of this important pathway in cortical and thalamic computations is not well …

The cerebral cortex integrates sensory information with emotional states and internal
representations to produce coherent percepts, form associations, and execute voluntary …

How neuronal circuits achieve credit assignment remains a central unsolved question in
systems neuroscience. Various studies have suggested plausible solutions for back …

Glutamatergic NMDA receptors (NMDAR) are critical for cognitive function, and their
reduced expression leads to intellectual disability. Since subpopulations of NMDARs exist in …

Higher-order sensory thalamic nuclei are densely connected with multiple cortical and
subcortical areas, yet the role of these nuclei remains elusive. The posteromedial thalamic …

The complete or partial damage of ascending somatosensory pathways produced by a
spinal cord injury triggers changes in the somatosensory cortex consisting in a functional …

The apical dendrites of layer (L) 2/3 pyramidal neurons in the mouse somatosensory cortex
integrate synaptic input from long-range projections. Among those, inputs from the higher …

The posteromedial thalamus (POm) has extensive recurrent connectivity with the whisker-
related primary somatosensory cortex (wS1) of rodents. However, its functional contribution …