Fungal infections are on the rise, driven by a growing population at risk and climate change.
Currently available antifungals include only five classes, and their utility and efficacy in …

SUMMARY A significant increase in the incidence of Candida-mediated infections has been
observed in the last decade, mainly due to rising numbers of susceptible individuals …

Genomic copy number changes are associated with antifungal drug resistance and
virulence across diverse fungal pathogens, but the rate and dynamics of these genomic …

Fungi were some of the earliest organismal systems used to explore mutational processes
and its phenotypic consequences on members of a species. Yeasts that cause significant …

Candida albicans is a pathobiont in humans that forms part of the mycobiota in healthy
individuals and can cause different pathologies upon alterations of the host defenses. The …

RNA interference (RNAi) is a fundamental regulatory pathway with a wide range of
functions, including regulation of gene expression and maintenance of genome stability …

To manage and treat chronic fungal diseases effectively, we require an improved
understanding of their complexity. There is an increasing appreciation that chronic infection …

Antimicrobial drug resistance poses a global health threat, requiring a deeper
understanding of the evolutionary processes that lead to its emergence in pathogens …

The intestinal microbiome harbors fungi that pose a significant risk to human health as
opportunistic pathogens and drivers of inflammation. Inflammatory and autoimmune …

Candida albicans normally colonizes the human gastrointestinal tract as a commensal.
Studying fungal factors involved in colonizing the mammalian gastrointestinal tract requires …