Coenzyme A (CoA) is a ubiquitous essential cofactor that plays a central role in the
metabolism of carboxylic acids, including short-and long-chain fatty acids. In the last few …

The sulfonation of endogenous molecules is a pervasive biological phenomenon that is not
always easily understood, and although it is increasingly recognized as a function of …

The biosynthesis of CoA from pantothenic acid (vitamin B 5) is an essential universal
pathway in prokaryotes and eukaryotes. The CoA biosynthetic genes in bacteria have all …

The zinc finger protein Snail is a master regulator of epithelial–mesenchymal transition
(EMT) and a strong inducer of tumor metastasis, yet the signal cascades triggered by Snail …

phosphoadenosine 5'‐phosphosulfate (PAPS) synthase (PAPSS) catalyzes the biosynthesis
of PAPS which serves as the universal sulfonate donor compound for all sulfotransferase …

Sulfur is an essential element for all organisms. Plants must assimilate this nutrient from the
environment and convert it into metabolically useful forms for the biosynthesis of a wide …

ATP sulfurylases (ATPSs) are ubiquitous enzymes that catalyse the primary step of
intracellular sulfate activation: the reaction of inorganic sulfate with ATP to form adenosine …

The rising emergence of antibiotic resistance urges the search for new strategies to defeat
microorganisms that lead to persistent infections of the host. Tolerant to antibiotics, slowly …

Nicotinamide mononucleotide adenylyltransferase (NMNAT), a member of the
nucleotidyltransferase α/β-phosphodiesterases superfamily, catalyzes a universal step …

Phosphopantetheine adenylyltransferase (PPAT) is an essential enzyme in the coenzyme A
pathway that catalyzes the reversible transfer of an adenylyl group from ATP to 4 …