Melioidosis
Burkholderia pseudomallei is a Gram-negative environmental bacterium and the
aetiological agent of melioidosis, a life-threatening infection that is estimated to account …
aetiological agent of melioidosis, a life-threatening infection that is estimated to account …
CNS infection and immune privilege
JV Forrester, PG McMenamin, SJ Dando - Nature Reviews …, 2018 - nature.com
Classically, the CNS is described as displaying immune privilege, as it shows attenuated
responses to challenge by alloantigen. However, the CNS does show local inflammation in …
responses to challenge by alloantigen. However, the CNS does show local inflammation in …
SARS-CoV-2 receptors and entry genes are expressed in the human olfactory neuroepithelium and brain
L Fodoulian, J Tuberosa, D Rossier, M Boillat, C Kan… - Iscience, 2020 - cell.com
Reports indicate an association between COVID-19 and anosmia, as well as the presence
of SARS-CoV-2 virions in the olfactory bulb. To test whether the olfactory neuroepithelium …
of SARS-CoV-2 virions in the olfactory bulb. To test whether the olfactory neuroepithelium …
Pathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasion
The brain is well protected against microbial invasion by cellular barriers, such as the blood-
brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). In addition, cells …
brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). In addition, cells …
Potential neuroinvasive pathways of SARS‐CoV‐2: Deciphering the spectrum of neurological deficit seen in coronavirus disease‐2019 (COVID‐19)
AM Baig, EC Sanders - Journal of medical virology, 2020 - Wiley Online Library
Abstract Coronavirus disease‐2019 (COVID‐19) was declared a global pandemic on 11
March 2020. Scientists and clinicians must acknowledge that severe acute respiratory …
March 2020. Scientists and clinicians must acknowledge that severe acute respiratory …
Melioidosis: evolving concepts in epidemiology, pathogenesis, and treatment
BJ Currie - Seminars in respiratory and critical care medicine, 2015 - thieme-connect.com
Infection with Burkholderia pseudomallei can result in asymptomatic seroconversion, a
single skin lesion that may or may not heal spontaneously, a pneumonia which can be …
single skin lesion that may or may not heal spontaneously, a pneumonia which can be …
Nose to brain drug delivery-a promising strategy for active components from herbal medicine for treating cerebral ischemia reperfusion
Y Long, Q Yang, Y Xiang, Y Zhang, J Wan, S Liu… - Pharmacological …, 2020 - Elsevier
Cerebral ischemia reperfusion injury (CIRI), one of the major causes of death from stroke in
the world, not only causes tremendous damage to human health, but also brings heavy …
the world, not only causes tremendous damage to human health, but also brings heavy …
Chlamydia pneumoniae can infect the central nervous system via the olfactory and trigeminal nerves and contributes to Alzheimer's disease risk
Chlamydia pneumoniae is a respiratory tract pathogen but can also infect the central
nervous system (CNS). Recently, the link between C. pneumoniae CNS infection and late …
nervous system (CNS). Recently, the link between C. pneumoniae CNS infection and late …
Antibiotic resistance in Burkholderia species
KA Rhodes, HP Schweizer - Drug Resistance Updates, 2016 - Elsevier
The genus Burkholderia comprises metabolically diverse and adaptable Gram-negative
bacteria, which thrive in often adversarial environments. A few members of the genus are …
bacteria, which thrive in often adversarial environments. A few members of the genus are …
Olfactory immunology: the missing piece in airway and CNS defence
SA Wellford, EA Moseman - Nature Reviews Immunology, 2024 - nature.com
The olfactory mucosa is a component of the nasal airway that mediates the sense of smell.
Recent studies point to an important role for the olfactory mucosa as a barrier to both …
Recent studies point to an important role for the olfactory mucosa as a barrier to both …