Survivin at a glance
SP Wheatley, DC Altieri - Journal of cell science, 2019 - journals.biologists.com
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is
essential for cell division and can inhibit cell death. Normally it is only expressed in actively …
essential for cell division and can inhibit cell death. Normally it is only expressed in actively …
[HTML][HTML] Aurora kinases: novel therapy targets in cancers
A Tang, K Gao, L Chu, R Zhang, J Yang, J Zheng - Oncotarget, 2017 - ncbi.nlm.nih.gov
Aurora kinases, a family of serine/threonine kinases, consisting of Aurora A (AURKA),
Aurora B (AURKB) and Aurora C (AURKC), are essential kinases for cell division via …
Aurora B (AURKB) and Aurora C (AURKC), are essential kinases for cell division via …
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis
M Carmena, M Wheelock, H Funabiki… - … reviews Molecular cell …, 2012 - nature.com
Successful cell division requires the precise and timely coordination of chromosomal,
cytoskeletal and membrane trafficking events. These processes are regulated by the …
cytoskeletal and membrane trafficking events. These processes are regulated by the …
The aurora kinases in cell cycle and leukemia
B Goldenson, JD Crispino - Oncogene, 2015 - nature.com
The Aurora kinases, which include Aurora A (AURKA), Aurora B (AURKB) and Aurora C
(AURKC), are serine/threonine kinases required for the control of mitosis (AURKA and …
(AURKC), are serine/threonine kinases required for the control of mitosis (AURKA and …
The Aurora B kinase in chromosome bi-orientation and spindle checkpoint signaling
V Krenn, A Musacchio - Frontiers in oncology, 2015 - frontiersin.org
Aurora B, a member of the Aurora family of serine/threonine protein kinases, is a key player
in chromosome segregation. As part of a macromolecular complex known as the …
in chromosome segregation. As part of a macromolecular complex known as the …
The cellular geography of aurora kinases
M Carmena, WC Earnshaw - Nature reviews Molecular cell biology, 2003 - nature.com
Aurora is the name given to a family of highly conserved protein kinases with essential roles
in many aspects of cell division. Yeasts have a single Aurora kinase, whereas mammals …
in many aspects of cell division. Yeasts have a single Aurora kinase, whereas mammals …
Regulation of HP1–chromatin binding by histone H3 methylation and phosphorylation
W Fischle, BS Tseng, HL Dormann, BM Ueberheide… - Nature, 2005 - nature.com
Tri-methylation of histone H3 lysine 9 is important for recruiting heterochromatin protein 1
(HP1) to discrete regions of the genome, thereby regulating gene expression, chromatin …
(HP1) to discrete regions of the genome, thereby regulating gene expression, chromatin …
VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo
EA Harrington, D Bebbington, J Moore… - Nature medicine, 2004 - nature.com
The Aurora kinases are essential for the regulation of chromosome segregation and
cytokinesis during mitosis. Aberrant expression and activity of these kinases occur in a wide …
cytokinesis during mitosis. Aberrant expression and activity of these kinases occur in a wide …
GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy
Identification of protein phosphorylation sites with their cognate protein kinases (PKs) is a
key step to delineate molecular dynamics and plasticity underlying a variety of cellular …
key step to delineate molecular dynamics and plasticity underlying a variety of cellular …
Roles of Aurora kinases in mitosis and tumorigenesis
J Fu, M Bian, Q Jiang, C Zhang - Molecular Cancer Research, 2007 - AACR
Neuroblastoma is the most common extracranial solid tumor of children. Neuroblastoma
tumors derive from the neural crest and synthesize neurotransmitters including the …
tumors derive from the neural crest and synthesize neurotransmitters including the …