Hepatitis B virus (HBV) is a para-retrovirus or retroid virus that contains a double-stranded
DNA genome and replicates this DNA via reverse transcription of a RNA pregenome. Viral …

Hepatitis B virus (HBV) remains a major medical problem affecting at least 257 million
chronically infected patients who are at risk of developing serious, frequently fatal liver …

Current antiviral agents can control but not eliminate hepatitis B virus (HBV), because HBV
establishes a stable nuclear covalently closed circular DNA (cccDNA). Interferon-α treatment …

Background & Aims Several steps in the HBV life cycle remain obscure because of a lack of
robust in vitro infection models. These steps include particle entry, formation and …

Hepatitis B virus (HBV) infection remains a major public health concern worldwide with
about 257 million individuals chronically infected. Current therapies can effectively control …

Hepatitis B virus (HBV) is a highly contagious pathogen that afflicts over a third of the world's
population, resulting in close to a million deaths annually. The formation and persistence of …

The template of hepatitis B virus (HBV) transcription, the covalently closed circular DNA
(cccDNA), plays a key role in the life-cycle of the virus and permits the persistence of …

With a yearly death toll of 880,000, hepatitis B virus (HBV) remains a major health problem
worldwide, despite an effective prophylactic vaccine and well-tolerated, effective antivirals …

The emergence and takeover of hepatitis B virus (HBV) variants carrying mutation (s) in the
preS/S genomic region is a fairly frequent event that may occur spontaneously or may be the …

Hepatitis B virus (HBV) infection of hepatocytes begins by binding to its cellular receptor
sodium taurocholate cotransporting polypeptide (NTCP), followed by the internalization of …