SARS-CoV-2 vaccination significantly reduces morbidity and mortality, but has less impact
on viral transmission rates, thus aiding viral evolution, and the longevity of vaccine-induced …

Background The effectiveness of SARS-CoV-2 vaccines in older adults living in long-term
care facilities is uncertain. We investigated the protective effect of the first dose of the Oxford …

Background Long-term care facilities (LTCFs) have reported high SARS-CoV-2 infection
rates and related mortality, but the proportion of infected people among those who have …

Due to its leading role in fighting infections, the human immune system has been the focus
of many studies in the context of Coronavirus disease 2019 (COVID-19). In a worldwide …

Vaccination constitutes the best long-term solution against Coronavirus Disease-2019;
however, vaccine-derived immunity may not protect all groups equally, and the durability of …

Background SARS-CoV-2 infection represents a major challenge for long-term care facilities
(LTCFs) and many residents and staff are seropositive following persistent outbreaks. We …

Background Research on the effectiveness of COVID-19 booster-based vaccine schedule is
ongoing and real-world data on vaccine effectiveness (VE) in comorbid patients are limited …

Background Older age and frailty are risk factors for poor clinical outcomes following SARS-
CoV-2 infection. As such, COVID-19 vaccination has been prioritised for individuals with …

Detailed characterisation of immune responses induced by COVID-19 vaccines rolled out in
India: COVISHIELDTM (CS) and COVAXIN®(CO) in a pre-exposed population is only …

Third-dose coronavirus disease 2019 vaccines are being deployed widely but their efficacy
has not been assessed adequately in vulnerable older people who exhibit suboptimal …