Otitis media is an inflammatory disorder of the middle ear caused by airways-associated
bacterial or viral infections. It is one of the most common childhood infections as globally …

Introduction: Moraxella catarrhalis is a prominent pathogen that causes acute otitis media in
children and lower respiratory tract infections in adults, resulting in a significant …

Moraxella catarrhalis is a human-restricted commensal that over the last two decades has
developed into an emerging respiratory tract pathogen. The bacterial species is equipped …

Objective To review the literature on progress regarding (1) effectiveness of vaccines for
prevention of otitis media (OM) and (2) development of vaccine antigens for OM bacterial …

Moraxella catarrhalis is the second most common cause of exacerbations in adults with
COPD, resulting in enormous morbidity and mortality in this clinical setting. Vaccine …

Published work has shown that glycoconjugate vaccines, based on truncated detoxified
lipopolysaccharides from Moraxella catarrhalis attached through their reducing end to a …

Understanding how immunity to pathogens develops is crucial for progress in the quest for
effective vaccines. Intraspecies and interspecies cross-reacting antibodies are produced in …

To investigate the vaccine potential of H. pylori lipopolysaccharide (LPS), truncated LPS of
H. pylori strain 26695 HP0826:: Kan lacking O-chain polysaccharide and comprising an …

Objective To update progress on the effectiveness of vaccine for prevention of acute otitis
media (AOM) and identification of promising candidate antigens against Streptococcus …

Oligosaccharide structures derived from the lipooligosaccharide of M. catarrhalis show that
the highly branched glucose-rich inner core of the oligosaccharide has an altered …