The expanding role of primary care in cancer control

G Rubin, A Berendsen, SM Crawford… - The lancet …, 2015 - thelancet.com
The nature of cancer control is changing, with an increasing emphasis, fuelled by public and
political demand, on prevention, early diagnosis, and patient experience during and after …

Improving early diagnosis of symptomatic cancer

W Hamilton, FM Walter, G Rubin… - Nature Reviews Clinical …, 2016 - nature.com
Much time, effort and investment goes into the diagnosis of symptomatic cancer, with the
expectation that this approach brings clinical benefits. This investment of resources has …

[HTML][HTML] The diagnostic performance of CA125 for the detection of ovarian and non-ovarian cancer in primary care: A population-based cohort study

G Funston, W Hamilton, G Abel, EJ Crosbie… - PLoS …, 2020 - journals.plos.org
Background The serum biomarker cancer antigen 125 (CA125) is widely used as an
investigation for possible ovarian cancer in symptomatic women presenting to primary care …

Rethinking diagnostic delay in cancer: how difficult is the diagnosis?

G Lyratzopoulos, J Wardle, G Rubin - Bmj, 2014 - bmj.com
Rethinking diagnostic delay in cancer: how difficult is the diagnosis? Page 1 Rethinking
diagnostic delay in cancer: how difficult is the diagnosis? OPEN ACCESS Georgios …

[HTML][HTML] Diagnostic performance of a faecal immunochemical test for patients with low-risk symptoms of colorectal cancer in primary care: an evaluation in the South …

SER Bailey, GA Abel, A Atkins, R Byford… - British Journal of …, 2021 - nature.com
Background The faecal immunochemical test (FIT) was introduced to triage patients with low-
risk symptoms of possible colorectal cancer in English primary care in 2017, underpinned by …

Clinical relevance of thrombocytosis in primary care: a prospective cohort study of cancer incidence using English electronic medical records and cancer registry data

SER Bailey, OC Ukoumunne, EA Shephard… - British Journal of …, 2017 - bjgp.org
Background Thrombocytosis (raised platelet count) is an emerging risk marker of cancer, but
the association has not been fully explored in a primary care context. Aim To examine the …

[HTML][HTML] Predictive value of inflammatory markers for cancer diagnosis in primary care: a prospective cohort study using electronic health records

J Watson, C Salisbury, J Banks, P Whiting… - British journal of …, 2019 - nature.com
Background Early identification of cancer in primary care is important and challenging. This
study examined the diagnostic utility of inflammatory markers (C-reactive protein, erythrocyte …

Who should be investigated for haematuria? Results of a contemporary prospective observational study of 3556 patients

WS Tan, A Feber, R Sarpong, P Khetrapal, S Rodney… - European urology, 2018 - Elsevier
There remains a lack of consensus among guideline relating to which patients require
investigation for haematuria. We determined the incidence of urinary tract cancer in a …

[HTML][HTML] Age and gender variations in cancer diagnostic intervals in 15 cancers: analysis of data from the UK Clinical Practice Research Datalink

NU Din, OC Ukoumunne, G Rubin, W Hamilton… - PloS one, 2015 - journals.plos.org
Background Time from symptomatic presentation to cancer diagnosis (diagnostic interval) is
an important, and modifiable, part of the patient's cancer pathway, and can be affected by …

Explaining variation in cancer survival between 11 jurisdictions in the International Cancer Benchmarking Partnership: a primary care vignette survey

PW Rose, G Rubin, R Perera-Salazar, SS Almberg… - BMJ open, 2015 - bmjopen.bmj.com
Objectives The International Cancer Benchmarking Partnership (ICBP) is a collaboration
between 6 countries and 12 jurisdictions with similar primary care-led health services. This …