Structural information of butyrylcholinesterase (BChE) and its variants associated with
several diseases are discussed here. Pure human BChE has been proved safe and effective …

The present article reviews published efforts to study acetylcholinesterase and
butyrylcholinesterase structure and function using computer-based modeling and simulation …

Zinc chloride mediated synthesis, density functional theory (DFT) studies and molecular
docking of new carboxamide derivatives containing sulphonamide functionality is reported …

The discovery of acetylcholinesterase inhibitors is important for the treatment of Alzheimer's
disease (AD), known as the most common type of dementia. Due to the side effects of …

Methods: A total of 2750 phytochemicals from different medicinal plants were selected for
this study. These plants grow naturally in the climate of Pakistan and India and have been …

In the landscape of epigenetic regulation, histone deacetylase 3 (HDAC3) has emerged as a
prominent therapeutic target for the design and development of candidate drugs against …

Butyrylcholinesterase (BuChE, EC 3.1. 1.8) is an important pharmacological target for
Alzheimer's disease (AD) treatment. However, the currently available BuChE inhibitor …

Alzheimer's disease (AD), a neurodegenerative condition associated with ageing, can occur.
AD gradually impairs memory and cognitive function, which leads to abnormal behavior …

Acute lung injury (ALI) and its serious form, the acute respiratory distress syndrome (ARDS)
are devastating diseases without effective chemotherapy. Exuberant or uncontrolled …

The inhibition of FMS-like tyrosine kinase 3 (FLT3) activity using small-molecule inhibitors
has emerged as a target-based alternative to traditional chemotherapy for the treatment of …