Prediction of response and other improvements on the limitations of recombinant human erythropoietin therapy in anemic cancer patients
Y Beguin - Haematologica, 2002 - haematologica.org
BACKGROUND AND OBJECTIVES: The majority of cancer patients suffer from chronic
anemia. While recombinant human erythropoietin (rHuEPO) offers many of the advantages …
anemia. While recombinant human erythropoietin (rHuEPO) offers many of the advantages …
Mechanisms involved in the induced differentiation of leukemia cells
Despite the remarkable progress achieved in the treatment of leukemias over the last
several years, many problems (multidrug resistance [MDR], cellular heterogeneity …
several years, many problems (multidrug resistance [MDR], cellular heterogeneity …
Platelets and platelet-like particles mediate intercellular RNA transfer
A Risitano, LM Beaulieu, O Vitseva… - Blood, The Journal of …, 2012 - ashpublications.org
The role of platelets in hemostasis and thrombosis is clearly established; however, the
mechanisms by which platelets mediate inflammatory and immune pathways are less well …
mechanisms by which platelets mediate inflammatory and immune pathways are less well …
Different promoter usage and multiple transcription initiation sites of the interleukin‐1 receptor‐related human ST2 gene in UT‐7 and TM12 cells
H Iwahana, K Yanagisawa, A Ito‐Kosaka… - European Journal of …, 1999 - Wiley Online Library
The ST2 gene encodes receptor‐like molecules that are very similar to the type I interleukin‐
1 receptor. Two distinct types of the ST2 gene products, ST2 (a soluble secreted form) and …
1 receptor. Two distinct types of the ST2 gene products, ST2 (a soluble secreted form) and …
CD36 and TLR interactions in inflammation and phagocytosis: implications for malaria
LK Erdman, G Cosio, AJ Helmers, D Gowda… - The Journal of …, 2009 - journals.aai.org
CD36 participates in macrophage internalization of a variety of particles, and has been
implicated in inflammatory responses to many of these ligands. To what extent CD36 …
implicated in inflammatory responses to many of these ligands. To what extent CD36 …
Presence and expression of a novel variant form of ST2 gene product in human leukemic cell line UT-7/GM
S Tominaga, K Kuroiwa, K Tago, H Iwahana… - Biochemical and …, 1999 - Elsevier
A novel variant cDNA from the human ST2 gene other than ST2 or ST2L was identified and
tentatively named ST2V. Alternative splicing inserts a new exon which leads to a change in …
tentatively named ST2V. Alternative splicing inserts a new exon which leads to a change in …
[HTML][HTML] Oxygen-dependent regulation of erythropoietin receptor turnover and signaling
P Heir, T Srikumar, G Bikopoulos, S Bunda… - Journal of Biological …, 2016 - ASBMB
von Hippel-Lindau (VHL) disease is a rare familial cancer predisposition syndrome caused
by a loss or mutation in a single gene, VHL, but it exhibits a wide phenotypic variability that …
by a loss or mutation in a single gene, VHL, but it exhibits a wide phenotypic variability that …
Activated, but not resting human Th2 cells, in contrast to Th1 and T regulatory cells, produce soluble ST2 and express low levels of ST2L at the cell surface
S Lécart, N Lecointe, A Subramaniam… - European journal of …, 2002 - Wiley Online Library
The T1/ST2 gene encodes, as a result of differential splicing, a cell surface protein
(transmembrane form of T1/ST2, ST2L) and a soluble, secreted, protein (ST2). Here, we …
(transmembrane form of T1/ST2, ST2L) and a soluble, secreted, protein (ST2). Here, we …
The effect of recombinant human erythropoietin on platelet counts is strongly modulated by the adequacy of iron supply
M Loo, Y Beguin - Blood, The Journal of the American Society …, 1999 - ashpublications.org
The effect of recombinant human erythropoietin (rHuEpo) on megakaryopoiesis remains
controversial. Treatment with rHuEpo in renal failure patients has been associated with a …
controversial. Treatment with rHuEpo in renal failure patients has been associated with a …
Construction of ELISA system to quantify human ST2 protein in sera of patients
K Kuroiwa, H Li, K Tago, H Iwahana, K Yanagisawa… - Hybridoma, 2000 - liebertpub.com
The human ST2 gene can be specifically induced by growth stimulation in fibroblastic cells,
and can also be induced by antigen stimulation in Th2 cells. The gene encodes a soluble …
and can also be induced by antigen stimulation in Th2 cells. The gene encodes a soluble …