[HTML][HTML] Structural insights into redox-active cysteine residues of the Src family kinases

DE Heppner - Redox Biology, 2021 - Elsevier
Abstract The Src Family Kinases (SFKs) are pivotal regulators of cellular signal transduction
and highly sought-after targets in drug discovery. Their actions within cells are controlled by …

Screening fructosamine-3-kinase (FN3K) inhibitors, a deglycating enzyme of oncogenic Nrf2: Human FN3K homology modelling, docking and molecular dynamics …

NM Beeraka, J Zhang, S Mandal, H Vikram PR, J Liu… - PLoS …, 2023 - journals.plos.org
Fructosamine-3-kinase (FN3K) is involved in the deglycation of Nrf2, a significant regulator
of oxidative stress in cancer cells. However, the intricate functional aspects of FN3K and Nrf2 …