BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

HB Cheng, X Cao, S Zhang, K Zhang… - Advanced …, 2023 - Wiley Online Library
The use of boron dipyrromethene (BODIPY) in biomedicine is reviewed. To open, its
synthesis and regulatory strategies are summarized, and inspiring cutting‐edge work in post …

Recent developments of BODIPY-based colorimetric and fluorescent probes for the detection of reactive oxygen/nitrogen species and cancer diagnosis

VN Nguyen, J Ha, M Cho, H Li, KMK Swamy… - Coordination Chemistry …, 2021 - Elsevier
Boron-dipyrromethene (BODIPY) platforms have been recognized as potential candidates
for a wide range of applications, especially for constructing fluorescent probes due to their …

Design and application of fluorescent probes to detect cellular physical microenvironments

J Ma, R Sun, K Xia, Q Xia, Y Liu, X Zhang - Chemical Reviews, 2024 - ACS Publications
The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …

Singlet oxygen “afterglow” therapy with NIR‐II fluorescent molecules

J Zou, L Li, J Zhu, X Li, Z Yang, W Huang… - Advanced …, 2021 - Wiley Online Library
Abstract Improving singlet oxygen (1O2) lifespan by fractionated delivery in dark and
hypoxic conditions is a better way to achieve enhanced phototherapeutic efficacy. Herein …

Activity‐based sensing: a synthetic methods approach for selective molecular imaging and beyond

KJ Bruemmer, SWM Crossley… - Angewandte Chemie …, 2020 - Wiley Online Library
Emerging from the origins of supramolecular chemistry and the development of selective
chemical receptors that rely on lock‐and‐key binding, activity‐based sensing (ABS)—which …

Recent progress in utilizing near-infrared J-aggregates for imaging and cancer therapy

S Xu, HW Liu, SY Huan, L Yuan… - Materials Chemistry …, 2021 - pubs.rsc.org
J-Aggregates are an interesting class of fluorophore aggregates, which are formed by highly
ordered assembled organic dyes. They have intriguing optical properties, including narrow …

Application of multifunctional small molecule fluorescent probe BODIPY in life science

L Yuan, Y Su, H Cong, B Yu, Y Shen - Dyes and Pigments, 2023 - Elsevier
BODIPY and its derivative multifunctional small molecule probes have become the darlings
in the field of biomedical materials due to its unique molecular structure, high brightness …

Electrophysiology, unplugged: imaging membrane potential with fluorescent indicators

P Liu, EW Miller - Accounts of chemical research, 2019 - ACS Publications
Conspectus Membrane potential is a fundamental biophysical property maintained by every
cell on earth. In specialized cells like neurons, rapid changes in membrane potential drive …

Near-Infrared Laser-Triggered In Situ Dimorphic Transformation of BF2-Azadipyrromethene Nanoaggregates for Enhanced Solid Tumor Penetration

Y Chen, XH Zhang, DB Cheng, Y Zhang, Y Liu, L Ji… - ACS …, 2020 - ACS Publications
The shape of a drug delivery system impacts its in vivo behavior such as circulation time,
accumulation, and penetration. Considering the advantages of functional dyes in …

Fused Cycloheptatriene–BODIPY Is a High-Performance Near-Infrared Probe to Image Tau Tangles

T Xie, Y Li, C Tian, C Yuan, B Dai, S Wang… - Journal of Medicinal …, 2022 - ACS Publications
Neurofibrillary tangles (NFTs), which are composed of abnormally hyperphosphorylated
Tau, are one of the main pathologic hallmarks of Alzheimer's disease and other tauopathies …