[HTML][HTML] Positive and negative regulation of insulin signaling by reactive oxygen and nitrogen species

N Bashan, J Kovsan, I Kachko… - Physiological …, 2009 - journals.physiology.org
Regulated production of reactive oxygen species (ROS)/reactive nitrogen species (RNS)
adequately balanced by antioxidant systems is a prerequisite for the participation of these …

Vitamin E supplementation in the treatment on nonalcoholic fatty liver disease (NAFLD): Evidence from an umbrella review of meta‐analysis on randomized controlled …

MY Wang, K Prabahar, MA Găman… - Journal of Digestive …, 2023 - Wiley Online Library
Objective We conducted this umbrella review of meta‐analysis on randomized controlled
trials to clarify the effects of vitamin E administration on alanine aminotransferase (ALT) …

Flaxseed supplementation improved insulin resistance in obese glucose intolerant people: a randomized crossover design

Y Rhee, A Brunt - Nutrition Journal, 2011 - Springer
Background Obesity leads to an increase in inflammation and insulin resistance. This study
determined antioxidant activity of flaxseed and its role in inflammation and insulin resistance …

[PDF][PDF] Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of …

R Vinayagamoorthi, Z Bobby, MG Sridhar - Journal of endocrinology, 2008 - Citeseer
The oxidative stress-sensitive c-Jun-N-terminal kinase (JNK) pathway is known to be
activated in diabetic condition and is involved in the progression of insulin resistance …

Effects of antioxidant supplementation on insulin sensitivity, endothelial adhesion molecules, and oxidative stress in normal-weight and overweight young adults

HK Vincent, CM Bourguignon, AL Weltman, KR Vincent… - Metabolism, 2009 - Elsevier
The objective of the study was to determine whether short-term antioxidant (AOX)
supplementation affects insulin sensitivity, endothelial adhesion molecule levels, and …

Effects of vitamin E treatment on peroxisome proliferator‐activated receptor‐α expression and insulin resistance in patients with non‐alcoholic steatohepatitis: results …

F Yakaryilmaz, S Guliter, B Savas… - Internal medicine …, 2007 - Wiley Online Library
Background: Insulin resistance (IR) is commonly associated with non‐alcoholic
steatohepatitis (NASH). Peroxisome proliferator‐activated receptor‐α (PPAR‐α) may also …

Accelerated endothelial dysfunction in mild prediabetic insulin resistance: the early role of reactive oxygen species

ER Duncan, SJ Walker, VA Ezzat… - American Journal …, 2007 - journals.physiology.org
Insulin resistance is well established as an independent risk factor for the development of
type 2 diabetes and cardiovascular atherosclerosis. Most studies have examined …

Vitamins D and E Stimulate the PI3K-AKT Signalling Pathway in Insulin-Resistant SK-N-SH Neuronal Cells

AS Zaulkffali, NN Md Razip, SS Syed Alwi, A Abd Jalil… - Nutrients, 2019 - mdpi.com
This study investigated the effects of vitamins D and E on an insulin-resistant model and
hypothesized that this treatment would reverse the effects of Alzheimer's disease (AD) and …

Opuntia dillenii (Ker Gawl.) Haw., Seeds Oil Antidiabetic Potential Using In Vivo, In Vitro, In Situ, and Ex Vivo Approaches to Reveal Its Underlying Mechanism of …

M Bouhrim, H Ouassou, S Boutahiri, NE Daoudi… - Molecules, 2021 - mdpi.com
Opuntia dillenii Ker Gawl. is one of the medicinal plants used for the prevention and
treatment of diabetes mellitus (DM) in Morocco. This study aims to investigate the …

Evaluation of antidiabetic properties of cactus pear seed oil in rats

A Berraaouan, A Ziyyat, H Mekhfi, A Legssyer… - Pharmaceutical …, 2014 - Taylor & Francis
Abstract Context: Cactus pear (Opuntia ficus-indica (L.) Mill.(Cactaceae)) is a medicinal
plant widely used to treat diabetes. Objective: This work investigates the hypoglycemic and …