Improving the solubility and permeability of drugs via cocrystallization is an important theme
in crystal engineering with practical applications for the discovery and development of high …

Permeability of any pharmaceutical is critically significant for its biopharmaceutical profile,
therapeutic activities, and deciding its dosing regimen. Approximately 35% of the marketed …

Abacavir (ABC) is a carbocyclic 2′-deoxyguanosine nucleoside reverse transcriptase
inhibitor specifically prescribed for the treatment of HIV infection. However, as a BCS class III …

Acefylline (ACF) is a stimulant xanthine derivative drug, which is formulated as a piperazine
salt for the treatment of bronchial asthma. ACF falls under BCS class IV category of low …

Favipiravir (FPV) is used in the treatment of viral influenza, but it faces challenges due to its
moderate solubility and poor tabletability. As an oral drug, it is necessary to develop a drug …

Pirfenidone is an important drug molecule used in the treatment of idiopathic lung fibrosis.
Although approved by the USFDA in 2014, pirfenidone's aqueous solubility is too high and …

Allopurinol is a xanthine oxidase inhibitor with poor solubility and permeability, which
severely limit its drug absorption following the administration of some dosage forms, such as …

Emtricitabine (ECB), a nucleoside reverse-transcriptase inhibitor, is commonly used to
prevent and treat HIV infection in both adults and children. The drug is categorized as a …

It is well known that daidzein has various significant medicinal values and health benefits,
such as anti-oxidant, anti-inflammatory, anti-cancer, anti-diabetic, cholesterol lowering …

The increasing worldwide cancer prevalence is a result of population aging and expansion
and changes in individuals' exposure to risk factors, many of which are linked to …