The presence, magnitude, and significance of sex differences in the human brain are hotly
debated topics in the scientific community and popular media. This debate is largely fueled …

Predictive biomarkers are the mainstay of precision medicine. This review summarizes the
advancements in tissue-based diagnostic biomarkers for gastric cancer, which is considered …

The immune systems of post-pubescent males and females differ significantly with profound
consequences to health and disease. In many cases, sex-specific differences in the immune …

Background: Sex dimorphism strongly impacts tumor biology, with most cancers having a
male predominance. Uniquely, thyroid cancer (TC) is the only nonreproductive cancer with …

Sex/gender significantly contribute to shape the immune responses, contributing to
differences in the pathogenesis of infectious diseases in males and females, the response to …

The global burden of cancer is growing and a wide disparity in the incidence, malignancy
and mortality of different types of cancer between each sex has been demonstrated. The sex …

Menstrual disorders, infertility and premature menopause are common but often
underrecognized phenomena among women with chronic kidney disease. Hypothalamic …

Most writing on sexual differentiation of the mammalian brain (including our own) considers
just two organs: the gonads and the brain. This perspective, which leaves out all other body …

Nowadays, several types of tumors can benefit from the new frontier of immunotherapy, due
to the recent increasing knowledge of the role of the immune system in cancer control …

Background Estrogen signaling is indispensable for muscle regeneration, yet the role of
estrogen in the development of muscle inflammation, especially in the intramuscular T cell …