[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …
commercial point of view. In order to reach the systemic circulation after oral administration …
Nanoparticle-based delivery systems for vaccines
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …
vaccinations may have low immunogenicity and, in most situations, only provide partial …
[HTML][HTML] Nanostructured lipid carriers (NLCs) as drug delivery platform: Advances in formulation and delivery strategies
M Elmowafy, MM Al-Sanea - Saudi Pharmaceutical Journal, 2021 - Elsevier
NLCs have provoked the incessant impulsion for the development of safe and valuable drug
delivery systems owing to their exceptional physicochemical and then biocompatible …
delivery systems owing to their exceptional physicochemical and then biocompatible …
Lipid nanoparticles: Different preparation techniques, characterization, hurdles, and strategies for the production of solid lipid nanoparticles and nanostructured lipid …
P Ganesan, D Narayanasamy - Sustainable Chemistry and Pharmacy, 2017 - Elsevier
The bioavailability of an orally administered drug primarily depends on its solubility in the
GIT and its permeability across cell membranes. Also, a drug in solution form is preferred for …
GIT and its permeability across cell membranes. Also, a drug in solution form is preferred for …
[HTML][HTML] Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics
Central nervous system (CNS) disorders (eg, multiple sclerosis, Alzheimer's disease, etc.)
represent a growing public health issue, primarily due to the increased life expectancy and …
represent a growing public health issue, primarily due to the increased life expectancy and …
[HTML][HTML] Recent advances in oral delivery of drugs and bioactive natural products using solid lipid nanoparticles as the carriers
Chemical and enzymatic barriers in the gastrointestinal (GI) tract hamper the oral delivery of
many labile drugs. The GI epithelium also contributes to poor permeability for numerous …
many labile drugs. The GI epithelium also contributes to poor permeability for numerous …
Oral delivery of anticancer drugs: challenges and opportunities
The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …
significance of oral delivery in cancer therapeutics has been highlighted which principally …
Nanostructured lipid carriers: a promising drug carrier for targeting brain tumours
Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …
the pharmaceutical industry with the development of novel drug delivery systems that …
Pharmaceutical dispersion techniques for dissolution and bioavailability enhancement of poorly water-soluble drugs
X Zhang, H Xing, Y Zhao, Z Ma - Pharmaceutics, 2018 - mdpi.com
Over the past decades, a large number of drugs as well as drug candidates with poor
dissolution characteristics have been witnessed, which invokes great interest in enabling …
dissolution characteristics have been witnessed, which invokes great interest in enabling …
Solid lipid nanoparticles for oral drug delivery: chitosan coating improves stability, controlled delivery, mucoadhesion and cellular uptake
The poor stability of solid lipid nanoparticles (SLN) under acidic condition resulted in large
aggregation in gastric environment, limiting their application as oral delivery systems. In this …
aggregation in gastric environment, limiting their application as oral delivery systems. In this …