Background The optimal haemoglobin threshold for use of red blood cell (RBC) transfusions
in anaemic patients remains an active field of research. Blood is a scarce resource, and in …

Transfusion Medicine is a dynamically evolving field. Recent high-quality research has
reshaped the paradigms guiding blood transfusion. As increasing evidence supports the …

The COVID-19 pandemic has major implications for blood transfusion. There are uncertain
patterns of demand, and transfusion institutions need to plan for reductions in donations and …

For 30 years, transfusion-associated circulatory overload (TACO) has been recognized as a
serious transfusion complication. Currently, TACO is the leading cause of transfusion-related …

Red blood cells (RBCs) are exposed to both external and internal sources of oxidants that
challenge their integrity and compromise their physiological function and supply of oxygen …

Transfusion associated circulatory overload (TACO) is one of the leading causes of
transfusion related morbidity and mortality. TACO is the result of hydrostatic pulmonary …

Iron is an essential micronutrient for early development, being involved in several cellular
processes and playing a significant role in neurodevelopment. Prematurity may impact on …

An impressive effect of the infection with SARS-Co-19 is the impairment of oxygen uptake
due to lung injury. The reduced oxygen diffusion may potentially be counteracted by an …

The allosteric transition within tetrameric hemoglobin (Hb) that allows both full binding to
four oxygen molecules in the lung and full release of four oxygens in hypoxic tissues would …

Red blood cell (RBC) transfusion is one of the most common therapeutic procedures in
modern medicine. Although frequently lifesaving, it often has deleterious side effects. RBC …