Physiological data demonstrates theta frequency oscillations associated with memory
function and spatial behavior. Modeling and data from animals provide a perspective on the …

Neurotrophins have been intensively studied and have multiple roles in the brain.
Neurotrophins are first synthetized as proneurotrophins and then cleaved intracellularly and …

Alzheimer's disease (AD) manifests with memory loss and spatial disorientation. AD
pathology starts in the entorhinal cortex, making it likely that local neural correlates of spatial …

Cellular membrane potential plays a key role in the formation and retrieval of memories in
the metazoan brain, but it remains unclear whether such memory can also be encoded in …

A goal‐directed navigation model is proposed based on forward linear look‐ahead probe of
trajectories in a network of head direction cells, grid cells, place cells and prefrontal cortex …

This article presents a model of grid cell firing based on the intrinsic persistent firing shown
experimentally in neurons of entorhinal cortex. In this model, the mechanism of persistent …

We present a model that describes the generation of the spatial (grid fields) and temporal
(phase precession) properties of medial entorhinal cortical (MEC) neurons by combining …

The definition of episodic memory includes the concept of mental time travel: the ability to re-
experience a previously experienced trajectory through continuous dimensions of space …

Grid cells in the dorsal segment of the medial entorhinal cortex (dMEC) show remarkable
hexagonal activity patterns, at multiple spatial scales, during spatial navigation. It has …

A major tool in understanding how the brain processes information is the analysis of
neuronal output at each hierarchical level along the pathway of signal propagation. Theta …