Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …

B cells occupy a vital role in the functioning of the immune system, working in tandem with T
cells to either suppress or promote tumor growth within the tumor microenvironment (TME) …

Tumors are not isolated entities, but complex systemic networks involving cell-cell
communication between transformed and non-transformed cells. The milieu created by …

Exosomes are cell-derived vesicles containing heterogeneous active biomolecules such as
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …

The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has
been demonstrated in a multitude of different in vitro cell systems and in a variety of body …

The use of extracellular vesicles, specifically exosomes, as carriers of biomarkers in
extracellular spaces has been well demonstrated. Despite their promising potential, the use …

The innate immune system plays a crucial role in the host defense against viral and
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …

Extracellular vesicles (EVs) are under evaluation as therapeutics or as vehicles for drug
delivery. Preclinical studies of EVs often use mice or other animal models to assess efficacy …

Mesenchymal stem (stromal) cells (MSCs) are multipotent cells with the ability to differentiate
into several cell types, thus serving as a cell reservoir for regenerative medicine. Much of the …

Extracellular vesicles (EVs) are secreted by almost all cells. They contain proteins, lipids,
and nucleic acids which are delivered from the parent cells to the recipient cells. Thereby …