A review of the clinical utility of serum S100B protein levels in the assessment of traumatic brain injury

EP Thelin, DW Nelson, BM Bellander - Acta neurochirurgica, 2017 - Springer
Background In order to improve injury assessment of brain injuries, protein markers of
pathophysiological processes and tissue fate have been introduced in the clinic. The most …

Predictive value of S-100β protein for prognosis in patients with moderate and severe traumatic brain injury: systematic review and meta-analysis

E Mercier, A Boutin, F Lauzier, DA Fergusson… - Bmj, 2013 - bmj.com
Objectives To determine the ability and accuracy of the S-100β protein in predicting
prognosis after a moderate or severe traumatic brain injury. Design Systematic review and …

Serum S-100B concentration provides additional information fot the indication of computed tomography in patients after minor head injury: a prospective multicenter …

P Biberthaler, U Linsenmeier, KJ Pfeifer, M Kroetz… - Shock, 2006 - journals.lww.com
Ninety percent of patients with minor head injury (MHI) who have cranial computed
tomography (CCT) under the present clinical decision rules have normal scans. Serum …

S100-B protein as a screening tool for the early assessment of minor head injury

D Zongo, R Ribéreau-Gayon, F Masson… - Annals of emergency …, 2012 - Elsevier
STUDY OBJECTIVE: A computed tomography (CT) scan has high sensitivity in detecting
intracranial injury in patients with minor head injury but is costly, exposes patients to high …

S100B is an important outcome predictor in traumatic brain injury

EP Thelin, L Johannesson, D Nelson… - Journal of …, 2013 - liebertpub.com
The objective of the study was to examine how S100B, a biomarker of traumatic brain injury
(TBI), contributes to outcome prediction after adjusting for known parameters, including age …

Rapid elimination of protein S-100B from serum after minor head trauma

W Townend, C Dibble, K Abid, A Vail… - Journal of …, 2006 - liebertpub.com
Protein S-100B is released into the circulation after traumatic brain injury, and its serum
concentration relates to measures of injury severity and outcome. These properties have led …

The prognostic value of NSE and S100B from serum and cerebrospinal fluid in patients with spontaneous subarachnoid hemorrhage

S Moritz, J Warnat, S Bele, BM Graf… - Journal of …, 2010 - journals.lww.com
Neuron-specific enolase (NSE) and S100B protein have been shown to be increased in
cerebrospinal fluid (CSF) and serum of patients suffering from subarachnoid hemorrhage …

Role of S100B protein in urine and serum as an early predictor of mortality after severe traumatic brain injury in adults

A Rodríguez-Rodríguez, JJ Egea-Guerrero… - Clinica chimica acta, 2012 - Elsevier
S100B is a calcium-binding protein released into the blood from astroglial cells due to brain
injury. Some authors have described a correlation between S100B serum concentration and …

The use of serum biomarkers to predict outcome after traumatic brain injury in adults and children

RP Berger - The Journal of head trauma rehabilitation, 2006 - journals.lww.com
Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in adults and
children. Predicting outcome after TBI is difficult, but it is important for acute management …

Serum S-100B protein as a molecular marker in severe traumatic brain injury

A Raabe, O Kopetsch, A Woszczyk… - Restorative …, 2003 - content.iospress.com
Purpose: There is growing evidence that S-100B protein may be used as a novel
biochemical marker of brain cell damage, measured by a simple blood test. In this paper, we …