Obesity-related hypogonadism in women

PC Eng, M Phylactou, A Qayum, C Woods… - Endocrine …, 2024 - academic.oup.com
Obesity-related hypogonadotropic hypogonadism is a well-characterized condition in men
(termed male obesity-related secondary hypogonadism; MOSH); however, an equivalent …

Neuroendocrine determinants of polycystic ovary syndrome

A Szeliga, E Rudnicka, M Maciejewska-Jeske… - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women and a
major cause of anovulatory infertility. A diagnosis of PCOS is established based the …

The emerging therapeutic potential of kisspeptin and neurokinin B

B Patel, K Koysombat, EG Mills, J Tsoutsouki… - Endocrine …, 2024 - academic.oup.com
Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …

[PDF][PDF] Assessing hypothalamic pituitary gonadal function in reproductive disorders

K Koysombat, WS Dhillo, A Abbara - Clinical Science, 2023 - portlandpress.com
Reproductive conditions secondary to disorders of the hypothalamic–pituitary–gonadal
(HPG) axis are common and are associated with important health implications and …

Treatments targeting neuroendocrine dysfunction in polycystic ovary syndrome (PCOS)

A Garg, B Patel, A Abbara, WS Dhillo - Clinical endocrinology, 2022 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of
reproductive age and is the leading cause of anovulatory subfertility. Increased …

Kisspeptin-neuron control of LH pulsatility and ovulation

H Stevenson, S Bartram, MM Charalambides… - Frontiers in …, 2022 - frontiersin.org
Feedback from oestradiol (E2) plays a critical role in the regulation of major events in the
physiological menstrual cycle including the release of gonadotrophins to stimulate follicular …

Neuroendocrine disturbances in women with functional hypothalamic amenorrhea: an update and future directions

B Męczekalski, O Niwczyk, C Battipaglia, L Troia… - Endocrine, 2024 - Springer
Functional hypothalamic amenorrhea (FHA) is one of the most common causes of both
primary and secondary amenorrhea in women of reproductive age. It is characterized by …

[HTML][HTML] Neuroendocrine disturbances in women with functional hypothalamic amenorrhea: an update and future directions

B Męczekalski, O Niwczyk, C Battipaglia, L Troia… - …, 2024 - pmc.ncbi.nlm.nih.gov
Functional hypothalamic amenorrhea (FHA) is one of the most common causes of both
primary and secondary amenorrhea in women of reproductive age. It is characterized by …

[HTML][HTML] Circulating kisspeptin and anti-müllerian hormone levels, and insulin resistance in women with polycystic ovary syndrome: A systematic review, meta-analysis …

FR Pérez-López, L Ornat, MT López-Baena… - European Journal of …, 2021 - Elsevier
Objective This systematic review and meta-analysis aimed to summarize the available
evidence regarding circulating kisspeptin and anti-müllerian hormone (AMH) and the …

Targeting elevated GnRH pulsatility to treat polycystic ovary syndrome

A Abbara, WS Dhillo - The Journal of Clinical Endocrinology & …, 2021 - academic.oup.com
Polycystic ovary syndrome (PCOS) is the foremost cause of anovulatory subfertility affecting
3% to 13% of women. Increased gonadotropin-releasing hormone (GnRH) pulsatility is a …