Nuclear magnetic resonance (NMR) spectroscopy is a robust method, which can rapidly
analyze mixtures at the molecular level without requiring separation and/or purification …

Metabolomics experiments usually result in a large quantity of data. Univariate and
multivariate analysis techniques are routinely used to extract relevant information from the …

Diverse forms of unwanted signal variations in mass spectrometry-based metabolomics data
adversely affect the accuracies of metabolic profiling. A variety of normalization methods …

This review presents an overview of the dynamically developing field of mass spectrometry‐
based metabolomics. Metabolomics aims at the comprehensive and quantitative analysis of …

Metabolic phenotyping is an important tool in translational biomedical research. The
advanced analytical technologies commonly used for phenotyping, including mass …

In metabolomics, tissues typically are extracted by grinding in liquid nitrogen followed by the
stepwise addition of solvents. This is time-consuming and difficult to automate, and the …

Metabolomics is a dynamic and emerging research field, similar to proteomics,
transcriptomics and genomics in affording global understanding of biological systems. It is …

Metabolomics is the study of global metabolite profiles in a system (cell, tissue, or organism)
under a given set of conditions. The analysis of the metabolome is particularly challenging …

Metabolomic analysis of tissue samples can be applied across multiple fields including
medicine, toxicology, and environmental sciences. A thorough evaluation of several …

In untargeted metabolomics analysis, several factors (eg, unwanted experimental &
biological variations and technical errors) may hamper the identification of differential …