Cancer remains as one of the most significant health problems, with approximately 19
million people diagnosed worldwide each year. Chemotherapy is a routinely used method to …

Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

meso-methyl BODIPY photocages have recently emerged as an exciting new class of
photoremovable protecting groups (PPGs) that release leaving groups upon absorption of …

Photocages are light-sensitive chemical protecting groups that give investigators control
over activation of biomolecules using targeted light irradiation. A compelling application of …

Cathepsin B (CTSB), a lysosomal cysteine protease, plays an important role in human
physiology and pathology. CTSB is associated with various human diseases, and its …

Photopharmacological tools enable the precise spatiotemporal control of small molecule
drugs. Amongst them, caged compounds incorporate a photolabile moiety which is released …

Photoactivatable protecting groups (PPGs) or caged compounds are beneficial tools for
spatiotemporal controlled release of bioagents, fluorescent probes, polymerization initiators …

Targeted drug delivery has been extensively studied in the last decade, whereas both
passive and active targeting strategies still face many challenges, such as off‐target drug …

Photodynamic therapy (PDT) is a clinically approved cancer treatment that requires a
photosensitizer (PS), light, and molecular oxygen─ a combination which produces reactive …

BODIPY-based photocages release substrates by excitation with wavelengths in the visible
to near-IR regions. The recent development of more efficient BODIPY photocages spurred …