Perfluorinated and polyfluorinated compounds (PFASs) are a class of synthetic chemical
substances that are widely used in human production and life, such as fire-fighting foams …

The therapeutic potential of mesenchymal stromal cells (MSCs) in the treatment of liver
fibrosis is predominantly based on their immunosuppressive properties, and their ability to …

Cytokines are pivotal in the generation and resolution of the inflammatory response. The
midkine/pleiotrophin (MK/PTN) family of cytokines, composed of just two members, was …

Both Multipotent Adult Progenitor Cells and Mesenchymal Stromal Cells are bone-marrow
derived, non-haematopoietic adherent cells, that are well-known for having …

The expansion of follicular helper T (Tfh) cells, which is tightly associated with the
development of lupus, is reversed by the inhibition of either glycolysis or glutaminolysis in …

Perfluorooctanesulfonate (PFOS) is a man-made chemical widely used in industrial
products. Due to its high persistence, PFOS has been detected in most animal species …

A tumor represents a highly intricate tissue entity, characterized by an exceptionally complex
microenvironment that starkly contrasts with the typical physiological surroundings of healthy …

CD138 (syndecan 1), a member of the heparan-sulfate proteoglycan family, regulates
diverse biological responses by interacting with chemokines, cytokines, growth factors, and …

Cancer immunotherapy targets the interplay between immune and cancer cells. In particular,
interactions between cytotoxic T lymphocytes (CTLs) and cancer cells, such as PD-1 …

Modulators of syndecan-2, such as an antibody to syndecan-2 that cross-links syndecan-2
on the cell surface or a syndecan-2 polypeptide that interferes with syndecan-2 receptor …