Abstract The 1, 4‐conjugated addition of nitrogen centered nucleophiles to electron‐
deficient alkenes is one of the most significant and widely used reactions in modern …

This review summarizes methods of N-functionalization of imidazole and its derivatives
through simple aza-Michael addition. Apart from advances in the development of efficient …

An easy and efficient synthetic methodology for the one-pot stereocontrolled synthesis of
tetrahydroquinolines through Lewis acid activated Povarov reaction is described. The …

This works documents a new silica gel-supported nanocatalyst (Si@ NSBPdNPs 3) with low
Pd loadings for n-alkylation reactions at room temperature. Post synthesis characterisation …

The first example of an asymmetric aminocatalyzed aza-Michael addition of 1 H-indazole
derivatives to α, β-unsaturated aldehydes is described. The iminium/enamine cascade …

Conclusion: This review addresses most significant method for the synthesis of N-substituted
imidazole derivatives following Michael addition reaction of imidazole to α, β-unsaturated …

A lithium chloride catalyzed aza-Michael reaction of pyrazoles to α, β-unsaturated imides
has been developed. A range of aromatic and aliphatic α, β-unsaturated imides are found to …

A Cs 2 CO 3-catalyzed aza-Michael reaction of pyrazole to α, β-unsaturated ketones has
been developed. With 5 mol% Cs 2 CO 3 as catalyst, a series of β-N1-pyrazoly ketones were …

摘要发展了一种碳酸铯催化吡唑与α, β-不饱和酮的氮杂Michael 反应新方法. 在5 mol%
Cs2CO3 存在下, 于1, 4-二氧六环中回流反应7~ 12 h, 以86%~ 95% 的产率得到21 种β-(N1 …

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Open Chemistry Journal, 2018, 5, 3-00 3 1874-8422/18 2018 Bentham Open Open Chemistry …