Autophagy, inflammation, and immune dysfunction in the pathogenesis of pancreatitis
Pancreatitis is a common disorder with significant morbidity and mortality, yet little is known
about its pathogenesis, and there is no specific or effective treatment. Its development …
about its pathogenesis, and there is no specific or effective treatment. Its development …
Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome
M Bhatia, S Moochhala - The Journal of Pathology: A Journal of …, 2004 - Wiley Online Library
Inflammatory response leading to organ dysfunction and failure continues to be the major
problem after injury in many clinical conditions such as sepsis, severe burns, acute …
problem after injury in many clinical conditions such as sepsis, severe burns, acute …
Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality
H Choi, Y Kim, A Mirzaaghasi, J Heo, YN Kim… - Science …, 2020 - science.org
As extracellular vesicles that play an active role in intercellular communication by
transferring cellular materials to recipient cells, exosomes offer great potential as a natural …
transferring cellular materials to recipient cells, exosomes offer great potential as a natural …
[HTML][HTML] The interplay between inflammation, coagulation and endothelial injury in the early phase of acute pancreatitis: clinical implications
P Dumnicka, D Maduzia, P Ceranowicz… - International journal of …, 2017 - mdpi.com
Acute pancreatitis (AP) is an inflammatory disease with varied severity, ranging from mild
local inflammation to severe systemic involvement resulting in substantial mortality. Early …
local inflammation to severe systemic involvement resulting in substantial mortality. Early …
Inflammation, autophagy, and obesity: common features in the pathogenesis of pancreatitis and pancreatic cancer
Inflammation and autophagy are cellular defense mechanisms. When these processes are
deregulated (deficient or overactivated) they produce pathologic effects, such as oxidative …
deregulated (deficient or overactivated) they produce pathologic effects, such as oxidative …
Neutrophil extracellular traps induce trypsin activation, inflammation, and tissue damage in mice with severe acute pancreatitis
Background & Aims Neutrophils are involved in the development of acute pancreatitis (AP),
but it is not clear how neutrophil-induced tissue damage is regulated. In addition to secreting …
but it is not clear how neutrophil-induced tissue damage is regulated. In addition to secreting …
Role of immune cells and immune-based therapies in pancreatitis and pancreatic ductal adenocarcinoma
Immune cells are important in the pathogenesis of acute pancreatitis and determine disease
severity. Results from cytokine-based clinical trials for acute pancreatitis have been …
severity. Results from cytokine-based clinical trials for acute pancreatitis have been …
Acute pancreatitis: bench to the bedside
Acute pancreatitis is an acute inflammatory process of the pancreas that frequently involves
peripancreatic tissues and at times remote organ systems. The severity of the disease varies …
peripancreatic tissues and at times remote organ systems. The severity of the disease varies …
[HTML][HTML] Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis
M Leppkes, C Maueröder, S Hirth, S Nowecki… - Nature …, 2016 - nature.com
Ductal occlusion has been postulated to precipitate focal pancreatic inflammation, while the
nature of the primary occluding agents has remained elusive. Neutrophils make use of …
nature of the primary occluding agents has remained elusive. Neutrophils make use of …
Inflammation in acute and chronic pancreatitis
A Habtezion - Current opinion in gastroenterology, 2015 - journals.lww.com
Inflammation in acute and chronic pancreatitis : Current Opinion in Gastroenterology
Inflammation in acute and chronic pancreatitis : Current Opinion in Gastroenterology Log in or …
Inflammation in acute and chronic pancreatitis : Current Opinion in Gastroenterology Log in or …