[HTML][HTML] Extracellular vesicles as tools and targets in therapy for diseases

MA Kumar, SK Baba, HQ Sadida… - Signal transduction and …, 2024 - nature.com
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

[HTML][HTML] Extracellular vesicles as a translational approach for the treatment of COVID-19 disease: an updated overview

E Serretiello, A Ballini, A Smimmo, M Acunzo, M Raimo… - Viruses, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic
in the years 2020–2022. With a high prevalence, an easy route of transmission, and a long …

[HTML][HTML] Plant-derived extracellular vesicles as a delivery platform for RNA-based vaccine: feasibility study of an oral and intranasal SARS-CoV-2 vaccine

MAC Pomatto, C Gai, F Negro, L Massari… - Pharmaceutics, 2023 - mdpi.com
Plant-derived extracellular vesicles (EVs) may represent a platform for the delivery of RNA-
based vaccines, exploiting their natural membrane envelope to protect and deliver nucleic …

[HTML][HTML] Extracellular vesicles and their cells of origin: Open issues in autoimmune diseases

A Haghighitalab, M Dominici, MM Matin… - Frontiers in …, 2023 - frontiersin.org
The conventional therapeutic approaches to treat autoimmune diseases through
suppressing the immune system, such as steroidal and non-steroidal anti-inflammatory …

[HTML][HTML] Quantitative and functional characterisation of extracellular vesicles after passive loading with hydrophobic or cholesterol-tagged small molecules

G Tréton, C Sayer, M Schürz, M Jaritsch… - Journal of Controlled …, 2023 - Elsevier
Extracellular vesicles (EVs) are nanosized intercellular messengers that bear enormous
application potential as biological drug delivery vehicles. Much progress has been made for …

[HTML][HTML] The Yin and the Yang of extracellular vesicles during viral infections

C Martin, G Ligat, CE Malnou - Biomedical Journal, 2023 - Elsevier
The role of extracellular vesicles (EVs) as key players in the intercellular communication is a
subject of growing interest in all areas of physiology and pathophysiology, and the field of …

Therapeutic potential of RNA-enriched extracellular vesicles: the next generation in RNA delivery via biogenic nanoparticles

M Muskan, P Abeysinghe, R Cecchin, H Branscome… - Molecular Therapy, 2024 - cell.com
Exosomes are extracellular vesicles (EVs)(∼ 50–150 nm) that have emerged as promising
vehicles for therapeutic applications and drug delivery. These membrane-bound particles …

[HTML][HTML] MicroRNA signature from extracellular vesicles of HCV/HIV co-infected individuals differs from HCV mono-infected

V Cairoli, D Valle-Millares, MC Terrón-Orellano… - Journal of Molecular …, 2023 - Springer
Hepatitis C virus (HCV) coinfection with human immunodeficiency virus (HIV) has a
detrimental impact on disease progression. Increasing evidence points to extracellular …

[HTML][HTML] Extracellular Vesicles and Infection: From Hijacked Machinery to Therapeutic Tools

D Gonçalves, SN Pinto, F Fernandes - Pharmaceutics, 2023 - mdpi.com
Extracellular vesicles (EVs) comprise a broad range of secreted cell-derived membrane
vesicles. Beyond their more well-characterized role in cell communication, in recent years …

[HTML][HTML] Highly restrictive and directional penetration of the blood cerebral spinal fluid barrier by JCPyV

BA O'Hara, AS Lukacher, K Garabian… - PLoS …, 2024 - journals.plos.org
The human polyomavirus JCPyV is an opportunistic pathogen that infects greater than 60%
of the world's population. The virus establishes a persistent and asymptomatic infection in …