Although hormones such as glucocorticoids have been broadly accepted in recent decades
as general neuromodulators of memory processes, sex steroid hormones such as the potent …

The human menopause transition and aging are each associated with an increase in a
variety of health risk factors including, but not limited to, cardiovascular disease …

Sex differences in neurological disease extend from incidence, severity, progression and
symptoms and may ultimately influence treatment. Cognitive disturbances are frequent in …

There is ample empirical evidence to support the notion that the biological impacts of
estrogen extend beyond the gonads to other bodily systems, including the brain and …

This article is part of a Special Issue “Estradiol and Cognition”. There are sex differences in
hippocampus-dependent cognition and neurogenesis suggesting that sex hormones are …

The hippocampus is an area of the brain that undergoes dramatic plasticity in response to
experience and hormone exposure. The hippocampus retains the ability to produce new …

A promising strategy to delay and perhaps prevent Alzheimer's disease (AD) is to identify the
age-related changes that put the brain at risk for the disease. A significant normal age …

This review presents evidence for the idea that the expression of estrogen receptor alpha
and beta (ERα and ERβ) interacts with the level of estradiol (E2) to influence the etiology of …

BACKGROUND: Estrogens modulate the morphology and function of the hippocampus.
Recent studies have focused on the effects of different types of estrogens on neuroplasticity …

The pros and cons of estrogen therapy for use in postmenopausal women continue to be a
major topic of debate in women's health. Much of this debate focuses on the potential …