The prevalence of obesity has increased globally over the last 2 decades. Although the body
mass index has been a convenient and simple index of obesity at the population level …

Heart failure (HF) with preserved ejection fraction (EF; HFpEF) accounts for 50% of HF
cases, and its prevalence relative to HF with reduced EF continues to rise. In contrast to HF …

Aims Patients with heart failure and preserved ejection fraction (HFpEF) frequently have
difficult-to-control hypertension. We examined the effect of neprilysin inhibition on 'apparent …

Accumulating evidence points to the existence of an inflammatorymetabolic phenotype of
heart failure with a preserved ejection fraction (HFpEF), which is characterized by …

The prevalence of Type 2 Diabetes Mellitus (T2DM) is internationally ever-growing.
Therefore, prevention, diagnostics, and control of insulin resistance and T2DM are of …

Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous entity with
complex pathophysiology and manifestations. Phenomapping is the process of applying …

Adipose tissue is a dynamic organ in the endocrine system that can connect organs by
secreting molecules and bioactive. Hence, adipose tissue really plays a pivotal role in …

(BNP), and C-type natriuretic peptide (CNP) are the known members of the mammalian
natriuretic peptide system. The discovery of natriuretic peptides (NPs) dates back to 1981 …

Background: Few data are available comparing cardiovascular disease (CVD) biomarker
profiles between women and men in the general population. We analyzed sex-based …

The prevalence of obesity worldwide has increased in recent decades not only among
adults, but also in children and adolescents. This phenomenon contributes to an increased …