Simple Summary Chromatin and epigenetic alterations in cancer are responsible for a wide
range of transcriptional changes that link DNA mutations to tumor phenotype. In this review …

Biomarker discovery is at the heart of personalized treatment planning and cancer precision
therapeutics, encompassing disease classification and prognosis, prediction of treatment …

Heterogeneous response to Enzalutamide, a second-generation androgen receptor
signaling inhibitor, is a central problem in castration-resistant prostate cancer (CRPC) …

As a hot topic today, ferroptosis is closely involved in the progression and treatment of
cancer. Accordingly, we built a prognostic model around ferroptosis to predict the overall …

Introduction As a highly aggressive tumor with a poor prognosis, esophageal cancer
(ESCA)'s relationship with gene mutations is unclear. Therefore, we tried to explore the role …

Background Radioresistance is a major barrier to the successful treatment of head and neck
squamous cell carcinoma (HNSCC). Methods We took advantage of different types of data …

Objective The objective was to perform risk stratification of oropharyngeal cancer (OPC) for
treatment de‐escalation based on the radiomics analysis and human papillomavirus (HPV) …

Background In recent years, the availability of high throughput technologies, establishment
of large molecular patient data repositories, and advancement in computing power and …

Epigenetic clocks are valuable tools for estimating both chronological and biological age by
assessing DNA methylation levels at specific CpG dinucleotides. While conventional …

For a long time, the guidance for adjuvant chemoradiotherapy for lower grade glioma (LGG)
lacks instructions on the application timing and order of radiotherapy (RT) and …