Using ecological coexistence theory to understand antibiotic resistance and microbial competition

AD Letten, AR Hall, JM Levine - Nature ecology & evolution, 2021 - nature.com
Tackling antibiotic resistance necessitates deep understanding of how resource competition
within and between species modulates the fitness of resistant microbes. Recent advances in …

Evidence for long-term anthropogenic pollution: the hadal trench as a depository and indicator for dissemination of antibiotic resistance genes

H Yang, R Liu, H Liu, C Wang, X Yin… - Environmental …, 2021 - ACS Publications
Knowledge of the distribution and dissemination of antibiotic resistance genes (ARGs) is
essential for understanding anthropogenic impacts on natural ecosystems. The …

Антибиотикорезистентность в современном мире

ЛС Намазова-Баранова… - Педиатрическая …, 2017 - cyberleninka.ru
В статье поднимается актуальная не только для дальнейшего развития современной
медицины, но и затрагивающая интересы человечества в целом и каждого жителя …

Within-host dynamics shape antibiotic resistance in commensal bacteria

NG Davies, S Flasche, M Jit, KE Atkins - Nature ecology & evolution, 2019 - nature.com
The spread of antibiotic resistance, a major threat to human health, is poorly understood.
Simple population-level models of bacterial transmission predict that above a certain rate of …

Forecasting antimicrobial resistance evolution

J Rolff, S Bonhoeffer, C Kloft, R Leistner, R Regoes… - Trends in …, 2024 - cell.com
Antimicrobial resistance (AMR) is a major global health issue. Current measures for tackling
it comprise mainly the prudent use of drugs, the development of new drugs, and rapid …

Evolutionary epidemiology models to predict the dynamics of antibiotic resistance

F Blanquart - Evolutionary applications, 2019 - Wiley Online Library
The evolution of resistance to antibiotics is a major public health problem and an example of
rapid adaptation under natural selection by antibiotics. The dynamics of antibiotic resistance …

Rising pneumococcal antibiotic resistance in the post–13-valent pneumococcal conjugate vaccine era in pediatric isolates from a primary care setting

R Kaur, M Pham, KOA Yu… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background Antibiotic-resistant Streptococcus pneumoniae strains may cause
infections that fail to respond to antimicrobial therapy. Results reported from hospitalized …

What is the role of the environment in the emergence of novel antibiotic resistance genes? A modeling approach

J Bengtsson-Palme, V Jonsson… - Environmental Science & …, 2021 - ACS Publications
It is generally accepted that intervention strategies to curb antibiotic resistance cannot solely
focus on human and veterinary medicine but must also consider environmental settings …

Analysis of multiple bacterial species and antibiotic classes reveals large variation in the association between seasonal antibiotic use and resistance

DS Sun, SM Kissler, S Kanjilal, SW Olesen… - PLoS …, 2022 - journals.plos.org
Understanding how antibiotic use drives resistance is crucial for guiding effective strategies
to limit the spread of resistance, but the use–resistance relationship across pathogens and …

On the evolutionary ecology of multidrug resistance in bacteria

S Lehtinen, F Blanquart, M Lipsitch, C Fraser… - PLoS …, 2019 - journals.plos.org
Resistance against different antibiotics appears on the same bacterial strains more often
than expected by chance, leading to high frequencies of multidrug resistance. There are …