Background Major depression is a disabling psychiatric illness with complex origins. Life
stress (childhood adversity and recent stressful events) is a robust risk factor for depression …

BackgroundCortisol plays a multifaceted role in major depression disorder (MDD). Diurnal
rhythms are disturbed, there is increased resistance to the feedback action of …

Major depressive disorder (MDD) is a mood disorder that affects behavior and impairs
cognition. A gene potentially important to this disorder is the brain derived neurotrophic …

Adolescence is characterized by major biological, psychological, and social challenges, as
well as by an increase in depression rates. This review focuses on the association between …

Background Meta-analyses have yielded contradictory findings concerning the role of 5-
HTTLPR in interaction with stress (GxE) in depression. The current meta-analysis …

Increasing evidence supports the involvement of both heritable and environmental risk
factors in major depression (MD) and suicidal behavior (SB). Studies investigating gene …

Brain-derived neurotrophic factor (BDNF) is the most widely distributed neurotrophin in the
CNS, where it plays several pivotal roles in synaptic plasticity and neuronal survival. As a …

The burgeoning field of gene-by-environment (G× E) interactions has revealed fascinating
biological insights, particularly in the realm of stress-, anxiety-, and depression-related …

OBJECTIVES: The objectives of this study were as follows: to present a concise overview of
the sample, outcomes, determinants, non-response and attrition of the ongoing TRacking …

Positive affect has been implicated in the phenomenological experience of various
psychiatric disorders, vulnerability to develop psychopathology and overall socio-emotional …