Dendritic cells: translating innate to adaptive immunity

RM Steinman, H Hemmi - From innate immunity to immunological memory, 2006 - Springer
The innate immune system provides many ways to quickly resist infection. The twobest-
studieddefenses indendritic cells (DCs) are the productionof protective cytokines—like …

Innate, innate-like and adaptive lymphocytes in the pathogenesis of MS and EAE

L Van Kaer, JL Postoak, C Wang, G Yang… - Cellular & molecular …, 2019 - nature.com
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) in which the immune system damages the protective insulation surrounding the nerve …

IL-10–producing NKT10 cells are a distinct regulatory invariant NKT cell subset

D Sag, P Krause, CC Hedrick… - The Journal of …, 2014 - Am Soc Clin Investig
Invariant natural killer T (i NKT) cells rapidly produce copious amounts of multiple cytokines
after activation, thereby impacting a wide variety of different immune reactions. However …

Unconventional T cells in brain homeostasis, injury and neurodegeneration

M Lv, Z Zhang, Y Cui - Frontiers in Immunology, 2023 - frontiersin.org
The interaction between peripheral immune cells and the brain is an important component of
the neuroimmune axis. Unconventional T cells, which include natural killer T (NKT) cells …

Dendritic cells expand antigen‐specific Foxp3+CD25+CD4+ regulatory T cells including suppressors of alloreactivity

S Yamazaki, K Inaba, KV Tarbell… - Immunological …, 2006 - Wiley Online Library
Thymic derived naturally occurring CD25+ CD4+ T regulatory cells (Tregs) suppress
immune responses, including transplantation. Here we discuss the capacity of dendritic cells …

NKT cells: T lymphocytes with innate effector functions

L Van Kaer - Current opinion in immunology, 2007 - Elsevier
Natural killer T (NKT) cells are innate-like T lymphocytes that recognize glycolipid antigens
in the context of the MHC class I-related glycoprotein CD1d. Recent studies have identified …

Natural killer T cells and autoimmune disease

L Wu, LV Kaer - Current molecular medicine, 2009 - ingentaconnect.com
Natural killer T (NKT) cells are an unusual subset of innate immune cells that express a
surface receptor generated by somatic DNA rearrangement, a hallmark of cells of the …

Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction

S Yamazaki, M Patel, A Harper… - Proceedings of the …, 2006 - National Acad Sciences
Thymic-derived CD25+ CD4+ T regulatory cells (Tregs) suppress immune responses,
including transplantation. Here we evaluated the ability of dendritic cells (DCs) to expand …

The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells

CK Wan, J Oh, P Li, EE West, EA Wong, AB Andraski… - Immunity, 2013 - cell.com
Summary Interleukin-21 (IL-21) has broad actions on T and B cells, but its actions in innate
immunity are poorly understood. Here we show that IL-21 induced apoptosis of conventional …

The role of natural killer cells in the immune response in kidney transplantation

P Pontrelli, F Rascio, G Castellano… - Frontiers in …, 2020 - frontiersin.org
Natural killer cells (NK) represent a population of lymphocytes involved in innate immune
response. In addition to their role in anti-viral and anti-tumor defense, they also regulate …