Haemodialysis membranes

C Ronco, WR Clark - Nature Reviews Nephrology, 2018 - nature.com
Haemodialysis is an extracorporeal process in which the blood is cleansed via removal of
uraemic retention products by a semipermeable membrane. Traditionally, dialysis …

Clinical evidence on hemodiafiltration: a systematic review and a meta‐analysis

IM Mostovaya, PJ Blankestijn, ML Bots… - Seminars in …, 2014 - Wiley Online Library
In this review, a systematic literature search and meta‐analysis were performed to assess
the effects of hemodiafiltration (HDF) on clinical outcome, as compared with hemodialysis …

Performance of hemodialysis with novel medium cut-off dialyzers

AH Kirsch, R Lyko, LG Nilsson, W Beck… - Nephrology Dialysis …, 2017 - academic.oup.com
Background. Compared to high-flux dialysis membranes, novel medium cut-off (MCO)
membranes show greater permeability for larger middle molecules. Methods. In two …

Haemodiafiltration and mortality in end-stage kidney disease patients: a pooled individual participant data analysis from four randomized controlled trials

SAE Peters, ML Bots, B Canaud… - Nephrology Dialysis …, 2016 - academic.oup.com
Background Mortality rates remain high for haemodialysis (HD) patients and simply
increasing the HD dose to remove more small solutes does not improve survival. Online …

[HTML][HTML] Optimal convection volume for improving patient outcomes in an international incident dialysis cohort treated with online hemodiafiltration

B Canaud, C Barbieri, D Marcelli, F Bellocchio… - Kidney International, 2015 - Elsevier
Online hemodiafiltration (OL-HDF), the most efficient renal replacement therapy, enables
enhanced removal of small and large uremic toxins by combining diffusive and convective …

Hemodiafiltration to address unmet medical needs ESKD patients

B Canaud, J Vienken, S Ash - … Journal of the American Society of …, 2018 - journals.lww.com
Hemodiafiltration combines diffusive and convective solute removal in a single therapy by
ultrafiltering 20% or more of the blood volume processed using a high-flux hemodialyzer …

Global prevalent use, trends and practices in haemodiafiltration

B Canaud, K Köhler, JM Sichart… - Nephrology Dialysis …, 2020 - academic.oup.com
Online haemodiafiltration (HDF) represents today the most advanced and innovative form of
renal replacement therapy (RRT). Recent controlled trials tend to prove its superiority over …

[HTML][HTML] The high-volume haemodiafiltration vs high-flux haemodialysis registry trial (H4RT): a multi-centre, unblinded, randomised, parallel-group, superiority study to …

FJ Caskey, S Procter, SJ MacNeill, J Wade, J Taylor… - Trials, 2022 - Springer
Background More than a third of the 65,000 people living with kidney failure in the UK attend
a dialysis unit 2–5 times a week to have their blood cleaned for 3–5 h. In haemodialysis …

Haemodiafiltration for all: are we CONVINCEd?

R Shroff, C Basile, F van der Sande… - Nephrology Dialysis …, 2023 - academic.oup.com
Nearly 4 million people in the world receive life-sustaining kidney replacement therapy, with
haemodialysis (HD) accounting for approximately 69% of all treatments [1]. Despite …

Effects of hemodiafiltration versus conventional hemodialysis in children with ESKD: the HDF, heart and height study

R Shroff, C Smith, B Ranchin, AK Bayazit… - Journal of the …, 2019 - journals.lww.com
Background Hypertension and cardiovascular disease are common in children undergoing
dialysis. Studies suggest that hemodiafiltration (HDF) may reduce cardiovascular mortality in …