Tailoring nanomaterials for targeting tumor‐associated macrophages
Advances in the field of nanotechnology together with an increase understanding of tumor
immunology have paved the way for the development of more personalized cancer immuno …
immunology have paved the way for the development of more personalized cancer immuno …
Progress on modulating tumor‐associated macrophages with biomaterials
M Sylvestre, CA Crane, SH Pun - Advanced Materials, 2020 - Wiley Online Library
Tumor‐associated macrophages (TAMs) are a complex and heterogeneous population of
cells within the tumor microenvironment. In many tumor types, TAMs contribute toward tumor …
cells within the tumor microenvironment. In many tumor types, TAMs contribute toward tumor …
The promising role of tumor-associated macrophages in the treatment of cancer
H Wang, X Wang, X Zhang, W Xu - Drug Resistance Updates, 2024 - Elsevier
Macrophages are important components of the immune system. Mature macrophages can
be recruited to tumor microenvironment that affect tumor cell proliferation, invasion and …
be recruited to tumor microenvironment that affect tumor cell proliferation, invasion and …
Nanomaterials targeting tumor associated macrophages for cancer immunotherapy
Tumor-associated macrophages (TAMs) play an important role in regulating tumor growth,
invasion and metastasis, and constitute approximately 50% of tumor mass. TAMs can exist …
invasion and metastasis, and constitute approximately 50% of tumor mass. TAMs can exist …
[HTML][HTML] Development of functional nanomedicines for tumor associated macrophages-focused cancer immunotherapy
X Wei, J Wang, M Liang, M Song - Theranostics, 2022 - ncbi.nlm.nih.gov
Clinical cancer immunotherapies are usually impeded by tumor immunosuppression driven
by tumor associated macrophages (TAMs). Thus, TAMs can be considered as a promising …
by tumor associated macrophages (TAMs). Thus, TAMs can be considered as a promising …
Leveraging macrophages for cancer theranostics
As fundamental immune cells in innate and adaptive immunity, macrophages engage in a
double-edged relationship with cancer. Dissecting the character of macrophages in cancer …
double-edged relationship with cancer. Dissecting the character of macrophages in cancer …
Functionalized nanoparticles targeting tumor-associated macrophages as cancer therapy
Y He, RF de Araújo Júnior, LJ Cruz, C Eich - Pharmaceutics, 2021 - mdpi.com
The tumor microenvironment (TME) plays a central role in regulating antitumor immune
responses. As an important part of the TME, alternatively activated type 2 (M2) macrophages …
responses. As an important part of the TME, alternatively activated type 2 (M2) macrophages …
Targeted delivery of zoledronate to tumor-associated macrophages for cancer immunotherapy
X Zang, X Zhang, H Hu, M Qiao, X Zhao… - Molecular …, 2019 - ACS Publications
Tumor-associated macrophages (TAMs) are recruited from circulatory monocytes by tumor-
derived factors, which differentiate into macrophages residing in the tumor …
derived factors, which differentiate into macrophages residing in the tumor …
Nanomedicine-based cancer immunotherapies developed by reprogramming tumor-associated macrophages
Tumor microenvironment is a complex ecosystem composed of tumor extracellular matrix,
fibroblasts, blood vessels, and immune cells, promoting tumor development by secreting …
fibroblasts, blood vessels, and immune cells, promoting tumor development by secreting …
Normalization of the tumor microvasculature based on targeting and modulation of the tumor microenvironment
Z Li, F Ning, C Wang, H Yu, Q Ma, Y Sun - Nanoscale, 2021 - pubs.rsc.org
Angiogenesis is an essential process for tumor development. Owing to the imbalance
between pro-and anti-angiogenic factors, the tumor vasculature possesses the …
between pro-and anti-angiogenic factors, the tumor vasculature possesses the …