[HTML][HTML] Recent developments in lactose blend formulations for carrier-based dry powder inhalation
GA Hebbink, M Jaspers, HJW Peters… - Advanced Drug Delivery …, 2022 - Elsevier
Lactose is the most commonly used excipient in carrier-based dry powder inhalation (DPI)
formulations. Numerous inhalation therapies have been developed using lactose as a …
formulations. Numerous inhalation therapies have been developed using lactose as a …
[HTML][HTML] A roadmap to pulmonary delivery strategies for the treatment of infectious lung diseases
Pulmonary drug delivery is a highly attractive topic for the treatment of infectious lung
diseases. Drug delivery via the pulmonary route offers unique advantages of no first-pass …
diseases. Drug delivery via the pulmonary route offers unique advantages of no first-pass …
The future of dry powder inhaled therapy: Promising or discouraging for systemic disorders?
Dry powder inhalation therapy has been shown to be an effective method for treating
respiratory diseases like asthma, Chronic Obstructive Pulmonary Diseases and Cystic …
respiratory diseases like asthma, Chronic Obstructive Pulmonary Diseases and Cystic …
Pulmonary drug delivery for acute respiratory distress syndrome
The acute respiratory distress syndrome (ARDS) is a life-threatening condition that causes
respiratory failure. Despite numerous clinical trials, there are no molecularly targeted …
respiratory failure. Despite numerous clinical trials, there are no molecularly targeted …
[HTML][HTML] Understanding the importance of capsules in dry powder inhalers
F Buttini, E Quarta, C Allegrini, F Lavorini - Pharmaceutics, 2021 - mdpi.com
Pulmonary drug delivery is currently the focus of research and development because of its
potential to produce maximum therapeutic benefit to patients by directing the drug straight to …
potential to produce maximum therapeutic benefit to patients by directing the drug straight to …
Scientific and regulatory activities initiated by the US Food and Drug Administration to foster approvals of generic dry powder inhalers: quality perspective
N El-Gendy, CM Bertha, M Abd El-Shafy… - Advanced Drug Delivery …, 2022 - Elsevier
Regulatory science for generic dry powder inhalation products worldwide has evolved over
the last decade. The revised draft guidance Metered Dose Inhaler (MDI) and Dry Powder …
the last decade. The revised draft guidance Metered Dose Inhaler (MDI) and Dry Powder …
A quality-by-design strategic approach for the development of bedaquiline-pretomanid nanoparticles as inhalable dry powders for TB treatment
Tuberculosis (TB) is caused by Mycobacterium tuberculosis (M. tb) and is the second
leading cause of death from an infectious disease globally. The disease mainly affects the …
leading cause of death from an infectious disease globally. The disease mainly affects the …
[HTML][HTML] Effect of different molecular weights of polyethylene glycol as a plasticizer on the formulation of dry powder inhaler capsules: Investigation of puncturing size …
RR Kalmer, A Karimi, M Golizadeh… - Arabian Journal of …, 2022 - Elsevier
Today, the principle of research and development is pulmonary drug delivery due to the
potential for maximizing therapeutic effects for patients by direct drug targeting the pathology …
potential for maximizing therapeutic effects for patients by direct drug targeting the pathology …
Recent advances in orthogonal analytical techniques for microstructural understanding of inhalable particles: present status and future perspective
The quick advancement in pulmonary medicines, delivery mechanisms, and inhaler device
techniques in the last few years has recommended that the microstructural understanding of …
techniques in the last few years has recommended that the microstructural understanding of …
[HTML][HTML] The role of capsule aperture size on the dispersion of carrier-based formulation at different air flowrates
P Tang, M Kakhi, A Albariqi, SRB Behara… - International Journal of …, 2023 - Elsevier
The effect of capsule aperture size on the aerosol performance of lactose blend formulation
was studied using Foradil®(containing 12 μg of formoterol fumarate (FF 1) and 24 mg of …
was studied using Foradil®(containing 12 μg of formoterol fumarate (FF 1) and 24 mg of …