[HTML][HTML] Hormone replacement therapy in young women with primary ovarian insufficiency and early menopause

SD Sullivan, PM Sarrel, LM Nelson - Fertility and sterility, 2016 - Elsevier
Primary ovarian insufficiency (POI) is a rare but important cause of ovarian hormone
deficiency and infertility in women. In addition to causing infertility, POI is associated with …

[HTML][HTML] Premature Ovarian Insufficiency-an update on recent advances in understanding and management

S Torrealday, P Kodaman, L Pal - F1000Research, 2017 - ncbi.nlm.nih.gov
Premature ovarian insufficiency is a complex and relatively poorly understood entity with a
myriad of etiologies and multisystem sequelae that stem from premature deprivation of …

Genetic insights into biological mechanisms governing human ovarian ageing

KS Ruth, FR Day, J Hussain, A Martínez-Marchal… - Nature, 2021 - nature.com
Reproductive longevity is essential for fertility and influences healthy ageing in women,, but
insights into its underlying biological mechanisms and treatments to preserve it are limited …

Penetrance of pathogenic genetic variants associated with premature ovarian insufficiency

S Shekari, S Stankovic, EJ Gardner, G Hawkes… - Nature Medicine, 2023 - nature.com
Premature ovarian insufficiency (POI) affects 1% of women and is a leading cause of
infertility. It is often considered to be a monogenic disorder, with pathogenic variants in~ 100 …

Guía de práctica clínica de la Sociedad Interamericana de Cardiología sobre prevención primaria de enfermedad cardiovascular en la mujer

MA Sueldo, MAM Rivera… - … de cardiología de …, 2022 - scielo.org.mx
Guía de práctica clínica de la Sociedad Interamericana de Cardiología sobre prevención
primaria de enfermedad cardiovascular en la mujer SciELO - Scientific Electronic Library …

Ovarian follicular theca cell recruitment, differentiation, and impact on fertility: 2017 update

JAS Richards, YA Ren, N Candelaria… - Endocrine …, 2018 - academic.oup.com
The major goal of this review is to summarize recent exciting findings that have been
published within the past 10 years that, to our knowledge, have not been presented in detail …

Reproductive ovarian testing and the alphabet soup of diagnoses: DOR, POI, POF, POR, and FOR

LM Pastore, MS Christianson, J Stelling… - Journal of assisted …, 2018 - Springer
There are large variations in the number of oocytes within each woman, and biologically, the
total quantity is at its maximum before the woman is born. Scientific knowledge is limited …

Current concepts in premature ovarian insufficiency

K Maclaran, N Panay - Women's health, 2015 - journals.sagepub.com
Premature ovarian insufficiency (POI) is a life-changing diagnosis, with profound physical
and psychological consequences. Unfortunately, there are many deficiencies in our …

A systematic review and evidence assessment of monogenic gene–disease relationships in human female infertility and differences in sex development

A Van Der Kelen, Ö Okutman, E Javey… - Human …, 2023 - academic.oup.com
BACKGROUND As in other domains of medicine, high-throughput sequencing methods
have led to the identification of an ever-increasing number of gene variants in the fields of …

Dynamics of the ovarian reserve and impact of genetic and epidemiological factors on age of menopause

E Pelosi, E Simonsick, A Forabosco… - Biology of …, 2015 - academic.oup.com
The narrow standard age range of menopause,∼ 50 yr, belies the complex balance of
forces that govern the underlying formation and progressive loss of ovarian follicles (the …