[HTML][HTML] GLP-1 receptor agonists: beyond their pancreatic effects

X Zhao, M Wang, Z Wen, Z Lu, L Cui, C Fu… - Frontiers in …, 2021 - frontiersin.org
Glucagon like peptide-1 (GLP-1) is an incretin secretory molecule. GLP-1 receptor agonists
(GLP-1RAs) are widely used in the treatment of type 2 diabetes (T2DM) due to their …

[HTML][HTML] Glucagon-like peptide 1 (GLP-1)

TD Müller, B Finan, SR Bloom, D D'Alessio… - Molecular …, 2019 - Elsevier
Background The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …

Efficacy of GLP-1 RA approved for weight management in patients with or without diabetes: a narrative review

M Jensterle, M Rizzo, M Haluzík, A Janež - Advances in therapy, 2022 - Springer
The approval of once daily liraglutide, 3.0 mg, and once weekly semaglutide, 2.4 mg, for
chronic weight management provides a novel effective strategy against obesity. The reliable …

Relationship between perioperative semaglutide use and residual gastric content: a retrospective analysis of patients undergoing elective upper endoscopy

SQ Silveira, LM da Silva, ACV Abib… - Journal of clinical …, 2023 - Elsevier
Study objective Semaglutide is a long-acting glucagon-like peptide-1 receptor agonist used
for management of type 2 diabetes and/or obesity. To test the hypothesis that perioperative …

GLP-1 receptor agonists in non-alcoholic fatty liver disease: current evidence and future perspectives

R Nevola, R Epifani, S Imbriani, G Tortorella… - International Journal of …, 2023 - mdpi.com
To date, non-alcoholic fatty liver disease (NAFLD) is the most frequent liver disease,
affecting up to 70% of patients with diabetes. Currently, there are no specific drugs available …

Glucagon-like peptide 1 in health and disease

A Andersen, A Lund, FK Knop, T Vilsbøll - Nature Reviews …, 2018 - nature.com
In healthy individuals, the incretin hormone glucagon-like peptide 1 (GLP1) potentiates
insulin release and suppresses glucagon secretion in response to the ingestion of nutrients …

Management of endocrine disease: are all GLP-1 agonists equal in the treatment of type 2 diabetes?

MA Nauck, JJ Meier - European journal of endocrinology, 2019 - academic.oup.com
GLP-1, a peptide hormone secreted from the gut, stimulating insulin and suppressing
glucagon secretion was identified as a parent compound for novel treatments of diabetes …

Adipose tissue dysfunction and obesity-related male hypogonadism

VA Genchi, E Rossi, C Lauriola, R D'Oria… - International Journal of …, 2022 - mdpi.com
Obesity is a chronic illness associated with several metabolic derangements and
comorbidities (ie, insulin resistance, leptin resistance, diabetes, etc.) and often leads to …

Clinical recommendations to manage gastrointestinal adverse events in patients treated with Glp-1 receptor agonists: a multidisciplinary expert consensus

JJ Gorgojo-Martínez, P Mezquita-Raya… - Journal of Clinical …, 2022 - mdpi.com
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are indicated in type 2 diabetes and
obesity for their high efficacy in controlling glycaemia and inducing body weight loss …

Normal and disordered gastric emptying in diabetes: recent insights into (patho) physiology, management and impact on glycaemic control

RJ Jalleh, KL Jones, CK Rayner, CS Marathe, T Wu… - Diabetologia, 2022 - Springer
Gastric emptying is a major determinant of postprandial blood glucose, accounting for~ 35%
of variance in peak glucose in both healthy individuals and those with type 2 diabetes …