[HTML][HTML] Recent Trends and Potential of Radiotherapy in the Treatment of Anaplastic Thyroid Cancer

K Sekihara, H Himuro, S Toda, N Saito, R Hirayama… - Biomedicines, 2024 - mdpi.com
Anaplastic thyroid cancer (ATC) is a rare but highly aggressive malignancy characterized by
advanced disease at diagnosis and a poor prognosis. Despite multimodal therapeutic …

[HTML][HTML] Towards an era of precise diagnosis and treatment: Role of novel molecular modification-based imaging and therapy for dedifferentiated thyroid cancer

J Li, Y Zhang, F Sun, L Xing, X Sun - Frontiers in Endocrinology, 2022 - frontiersin.org
Dedifferentiated thyroid cancer is the major cause of mortality in thyroid cancer and is
difficult to treat. Hence, the essential molecular mechanisms involved in dedifferentiation …

[HTML][HTML] The genomic and evolutionary landscapes of anaplastic thyroid carcinoma

PYF Zeng, SD Prokopec, SY Lai, N Pinto… - Cell reports, 2024 - cell.com
Anaplastic thyroid carcinoma is arguably the most lethal human malignancy. It often co-
occurs with differentiated thyroid cancers, yet the molecular origins of its aggressivity are …

[HTML][HTML] Thyroglobulin expression, Ki-67 index, and lymph node ratio in the prognostic assessment of papillary thyroid cancer

H Lindfors, M Karlsen, E Karlton, J Zedenius… - Scientific Reports, 2023 - nature.com
The clinical significance of thyroglobulin (Tg) expression in papillary thyroid cancer (PTC)
has not been systematically explored in relation to the Ki-67 index, lymph node ratio (LNR) …

AKT-independent signaling in PIK3CA-mutant thyroid cancer mediates resistance to dual SRC and MEK1/2 inhibition

MM Rose, KW Nassar, V Sharma, RE Schweppe - Medical Oncology, 2023 - Springer
Anaplastic thyroid cancer (ATC) is a rare and aggressive disease with 90% of patients
succumbing to this disease 1 year after diagnosis. The approval of the combination therapy …

Study on chemical profiling of bailing capsule and its potential mechanism against thyroiditis based on network pharmacology with molecular docking strategy

M Wang, K Luo, B Bian, M Tian, H Zhao… - Biomedical …, 2024 - Wiley Online Library
Bailing capsule (BLC), a drug that is clinically administered to modulate the autoimmune
system, exhibits promising therapeutic potential in the treatment of thyroiditis. This study …

The Cooperative Signaling of Src and MAPK Pathways in Thyroid Cancer

MMK Rose - 2023 - search.proquest.com
Patients with advanced thyroid cancer, which include radioactive iodine-resistant (RAI-R)
differentiated thyroid cancer, poorly differentiated (PDTC), and anaplastic thyroid cancer …

[HTML][HTML] Rare distant metastases to pancreas, liver, and lung as initial presentation of mixed tall cell and columnar cell variants of papillary thyroid cancer

C Harper, J Michael, T Rahmeh… - … Diabetes & Metabolism …, 2022 - edm.bioscientifica.com
The most common sites of distant metastases of papillary thyroid carcinoma (PTC) are lung
and bone. Widespread distant metastases of PTC are rare and associated with poor overall …

[PDF][PDF] Next Generation Sequence-Based Targeted Somatic Mutation Analysis in Thyroid Nodules with Pathologically Diagnosed as Indeterminate Cytology

G Kök, D Nart, Y Ertan, SS Özbek, A Mizrak, Ö Makay… - 2024 - scholar.archive.org
Purpose: The management of indeterminate thyroid nodules remains a topic of ongoing
debate, particularly regarding the differentiation of malignancy. Somatic mutation analysis …

[HTML][HTML] Concurrent PIK3CA and TERT Mutation Promote the Proliferation and Invasion of Thyroid Carcinoma Cells and may be Caused by Up-regulating the …

H Duan, Q Ma, L Wang, S Wang… - Journal of …, 2023 - scientificarchives.com
Our previous research demonstrated that TERT and concurrent PIK3CA mutations predict
worse overall survival in patients with poorly differentiated thyroid carcinoma and anaplastic …